schizophrenia drugs Clozapine Flashcards
1
Q
what are the uses for Clozapine
A
Antipsychotic
2
Q
what is Clozapine effective against
A
+ve and -ve symptoms.
3
Q
what is its mechanism of action
5 answers
A
5HT2A receptors Antagonist action at muscarinic, 5HT2, alpha1 adrenoceptors, and H1 histamine receptors.
4
Q
what does it have a higher affinity for
A
Higher anity
for D4 than other dopamine receptors.
5
Q
what are Clozapine clinical uses
A
schiz
6
Q
what are Clozapine clinical uses
where is it used and why
A
patients resistant to other drugs
because of toxicity
7
Q
adverse effects
A
less EPS antimuscurinic action agranulocytosis sedation epileptic seizures weight gain hyperglycaemia
