schizophrenia drugs Chlorpromazine Flashcards
1
Q
first gen drugs
A
Chlorpromazine
Haloperidol
Flupentixol
2
Q
Chlorpromazine action
4
A
Antipsychotic.
Apathy and inertia.
Reduced aggression.
Antiemetic.
3
Q
Chlorpromazine MOA
A
Competitive antagonism of dopamine D2 receptors .
4
Q
Chlorpromazine MOA where
A
in the mesolimbic/mesocortical pathways
5
Q
Chlorpromazine MOA clinical benifits
and what does it suggest
A
delayed although receptor block is immediate, suggesting that slower changes in
neurotransmission occur.
6
Q
Chlorpromazine
what is it less affective against
A
Schizophrenia (less eective against –ve symptoms)
7
Q
Chlorpromazine
what else is it used for
A
tourette’s syndrome
8
Q
Chlorpromazine adverse effects
A
marked sedation
antimuscurinic action (parkinsons)
hypotension - alpha adrenoreceptor antagonist
