affective disorders NRI Reboxetine Flashcards
1
Q
what does reboxetine do and whats its MOA
A
antidepressant
inhibits selectively reuptake of Nor
no effect on 5-HT or dopamine
2
Q
when are the effects seen
A
not for a couple of weeks
indicating that other changes (eg down reg of receptor) are required for clinical effect
3
Q
clinical use of Reboxetine
A
depression
panic disorder
proposed for ADHD
4
Q
adverse effects of Reboxetine
A
insomnia
dues to antagonism of musc and his receptors = sweating and dry mouth
5
Q
what does this drug not do as a side effect
A
does not increase risk of young patient suicide
