schizophrenia drugs Amisulpride Flashcards
1
Q
what are the uses of Amisulpride
A
antipsychotic
2
Q
what is Amisulpride effective against
A
Eective against +ve and -ve symptoms of schizophrenia
3
Q
what does it bind to
A
D2 and D3 receptor antagonist
Low a
nity for 5HT,
histamine, muscarinic and alpha1 adrenergic receptors.
4
Q
what does Preferential action on dopamine autoreceptors explain
A
lower incidence of EPS and eectiveness against -ve symptoms
5
Q
clinical uses
A
schiz
6
Q
adverse effects
A
Hyperprolactinaemia. Insomnia.
Anxiety.
Weight gain.
Constipation and dry mouth.