schizophrenia drugs Amisulpride Flashcards

1
Q

what are the uses of Amisulpride

A

antipsychotic

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2
Q

what is Amisulpride effective against

A

Eective against +ve and -ve symptoms of schizophrenia

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3
Q

what does it bind to

A

D2 and D3 receptor antagonist
Low a…nity for 5HT,
histamine, muscarinic and alpha1 adrenergic receptors.

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4
Q

what does Preferential action on dopamine autoreceptors explain

A

lower incidence of EPS and eectiveness against -ve symptoms

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5
Q

clinical uses

A

schiz

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6
Q

adverse effects

A

Hyperprolactinaemia. Insomnia.
Anxiety.
Weight gain.
Constipation and dry mouth.

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