Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

General Pathology > Sample Questions from class Exam 2 > Flashcards

Sample Questions from class Exam 2 Flashcards

1
Q

holstein cattle and irish setter dogs have mutations in which molecules to develop leukocyte adhesion deficiency?

a. selectin
b. ICAM1
c. Integrin (CD18)
d. PECAM-1 (CD31)
e. siayl-lewis X glycoprotein

A

C. integrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

histamine increases vascular permeability at the level of capillaries and venules through the mechanism of

a. endothelial cell contraction
b. endothelial cell damage
c. increased transcytosis
d. induces endothelial proliferation

A

a. endothelial cell contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

an inflammatory cell that is long lived, can divide locally in tissue and regulates immune and repair responses

a. neutrophil
b. eosinophil
c. macrophage
d. platelet
e. B and C

A

c. macrophage (only cell that can divide locally in tissue!)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Neutrophil-endothelial surface molecules mediating “rolling”

a. integrin (CD11/CD18) - Selectin
b. sialyl lewis X - selectin
c. integrin (CD11/CD18) - ICAM1
d. PECAM1 (CD31) - PECAM1 (CD31)

A

B. sialyl lewis X - selectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

suppurative inflammatory reactions are often induced by

a. fungi
b. nematode parasites
c. bacteria (non-mycobacteria)
d. mycobacteria
e. toxins

A

c. bacteria (non-mycobacteria)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

eosinophilic inflammatory reactions are often induced by

a. fungi
b. nematode parasites
c. bacteria (non-mycobacteria)
d. mycobacteria
e. toxins

A

b. nematode parasites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

macrophage dominated (granulomatous) inflammatory reactions are often induced by:

a. fungi
b. nematode parasites
c. bacteria (non-mycobacteria)
d. mycobacteria
e. toxins

A

A and D. mycobacteria and fungi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which type of inflammatory cell is often associated iwth liquefactive necrosis?

a. lymphocyte
b. neutrophil
c. macrophages
d. eosinophil
e. mast cell

A

b. neutrophils (most effective at killing bacteria during acute infections)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q 
which of the followign have potenet chemotactic activity for neutrophils? 
a. C5a 
b. LTB4
C. IL8/CXCL8
D. A, B, C
E. B, C
A

D. All of them

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
which of the followign are potent mediators of increased vascular permeabilty? 
a. IL8/CXCL8
B. LTB4
C. Bradykinin
D. LTC4, LTD4, LTE4
E. A, C, D
F. C, D
A

F. bradykinin and LTC4, LTD4, LTE4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
which of the following mediate pain perception? 
a. PGE2
b. LTB4
C. Bradykinin
D. A, B, C
E. A, C
A

E. PGE2 and Bradykinin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

inciting stimuli of granulomatous inflammation are?
a. particulates resisting lysosomal degradation
b. persisting molecules that stimulate T cell hypersensitivity
c. stimuli that are chemotactic for macrophages and neutrophils
d. A and B
E. all

A

D. A, B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

granulomatous inflammation is almost always

a. acute
b. chronic

A

b. chronic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

inflammatory cells central to granulomatous inflammation?

a. macrophages
b. epithelial cells
c. multinucleated giant cells
d. all
e. A, C

A

E. A, C
Do not confuse epithelial with epithelioid

If epitheliod (modified macrophages) were a choice then it would be all

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

which conditions favor tissue repair by fibrosis follwoing injury?

a. lack of renewable cell population
b. prolonged/severe injury
c. minimal exudate
d. A, B
e. all

A

D. A, B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

which tissues are highly susceptible to repair by fibrosis or scarring bc they lack dividing renewable cell populations?

a. renal tubular epithelium
b. myocardial myocytes
c. cerebral cortical neurons
d. all
e. b, c

A

E. B, C

renal tubules do have renewing ability

17
Q 
ON EXAM! Which of the following are potent inducers of angiogenesis
a. VEGF
B. B-FGF
C. HGF
D. A, B
E All
A

D. A, B (VEGF and B-FGF)

18
Q 
which of the following is a potent inducer of fibrosis? 
a. TGF beta 
b. TNF alpha
C. PDGF
D. A, B 
E. All
A

E. ALL

19
Q 
type 1 anaphylactic hypersensitivity reactions can be mediated by 
a. IgG 
b. IgM 
C. IgE 
D. A, B 
E. A, C
A

E. A, C (IgG and IgE)

20
Q 
Which of the follwoing inflammatory mediators play a central role in anaphylaxis? 
a. histamine 
b. LTC4, LTD4, LTE4
c. C5a
D. A, B 
E. all
A

D. A, B

21
Q 
ON EXAM: type 3 hypersensitivity reactions can be mediated by: 
a. IgG 
b. IgM 
C. IgE 
D. A, B 
E. A, C
A

D. A, B

22
Q

Tissue injury in type 4 hypersensitivity/allergic reactions is mediated via?

a. immune complex formation
b. t cell induction of granulomatous inflammation
c. direct t cell cytotoxicity
d. all
e. B, C

A

E. B, C

23
Q

ON EXAM: type 3 immune complex hypersensitivity reactions occur most commonly in a state of?
A. Antigen excess
B. Antibody excess
c. antigen-antibody equivalence

A

A. Ag excess

General Pathology (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions