Salivary Glands and Lymphatics Flashcards
What drives latera and caudal folding
Mesoderm
What regulates the secretion of the lymphatic glands
motor and sensory nerves
Which nodes can you palpate for clinical assessment ?
Superficial Nodes
Which nodes are more difficult to palpate ?
Cervical deep lymph
Development of Lymph Nodes
6 steps
- Lymphatic Endothelial Cells leave the blood vessels
- LECs Aggregate to form Lymph sacs with groups of mesenchyme.
- Form the lymphatic nodules
- The nodules become surrounded by sinuses, with mesenchyme completing the lymph node. Start of the formation of cavities
- Lymphatic cells migrate from three different locations: Mesenchyme, Thymus (Pre birth), Marrow (Bone)
- Partition- A capsule (outside) and trabeculae (btwn the cell walls) surround the lymphatic nodules from surrounding mesenchyme.
Lymph node fluid is received from the
afferent lymphatic vessels
Filtered lymph collects in the
medulla
Fluid drains out the the lymph node via
efferent lymphatic vessel
at the hilum of the node
Are there more afferent or efferent lymphatic vessels?
Afferent ( slows down the flow of lymph)
Nodes are connected via
lymphatic vessels
Extracellular fluid is absorbed by lymph capillaries via
hydrostatic pressure
Lymph is filtered by
one or more lymph nodes before returning to venous circulation
The lymph node is surrounded by _______ and bands of connective tissue _______ extending from the capsule into the node
capsule, trabeculae
What is the purpose of the lymph capsule ?
dense connective tissue that protect the lymph
Tonsils can form from …
Lymph sacs
Tonsils are made from
- Un encapsulated Lymphatic tissue
2. covered in nonkeratinized stratified squamous epithelium
Empty acelluar portion of tonsils are called
Tonsillar crypts
Tonsilloliths
Tonsillar crypts can incase debris and calcifications
Which pouch does the tonsillar ring develop from?
Second pouch
Another name for Tonsillar Ring ?
Waldeyer’s Ring
Purpose of tonsillar ring ?
Immunologic protection, “First Pass” at the entrance of digestive and respiratory tracts
What are the four main tonsils in the ring ?
- Palantine
- Tubal
- phayngeal (adenoids)
- Lingual
Which tonsil is between palatophayngeal and palatoglossal
palantine
Which tonsil is in the lateral walls of the nasopharynx posterior to the auditory tube ?
Tubal
Which tonsil is at the roof of the nasopharynx?
Pharyngeal (adenoids)
Which tonsil is at the base of the tongue, posterior 2/3rds ?
Lingual
Why do we need saliva ?
- chemical break down of sugar
- Antibacterial Combat dryness
- Combat dryness
- Helps remineralize the tooth surface
Parotid gland develops from
step 1
step 2
an invagination of ectoderm between the maxillary and mandibular swelling
- Tubular ducts sink into the mesenchyme
- Duct opening in the mouth is transferred to the inner cheek via fusion of the max and mand swelling
Submandibular and sublingual glands form from …
form similar to how parotid gland forms but in the floor of the oral cavity
Forms from epithelial-mesenchymal interactions
Which are the major salivary glands
Parotid Gland
Submandibular
Sublingual Glands
Serous Secretion
thin, watery fluid
enzymes(amylases, peroxidases, lysozyme)
lactoferin
immunoglobulin A
Lactoferrin
Chelates iron needed for bacterial growth
Immunoglobulin A
Neutralizes bacteria and viruses
Muccous Secretion
Thick fluid
Mucins (glycoproteins)
Saliva composition
1-1.5L produced per day
Hypotonc solution (97% water containing)
Saliva Stimulation/Innervation
Parasympathetic- thin Saliva
Sympathetic- Thicker Mucous
Salivary Gland Histology
Made of epithelia and connective tissue (Encapsulated)
Acinar cells
Acinar cells
specialized to secret all the time
Salivary Ducts types
Intercalated Duct
Straited Duct
Excretory Duct
Intercalated Duct
- Receives fluid from acinus
2. simple cuboidal epithelium
Striated Duct
- Simple cuboidal to columnar epithelium
- Produces a hypotonic saliva (via reabsorbing NaCl)
- Secretes buffering bicarbonate into the saliva
Excretory Duct
- Connect to the oral cavity
- simple cuboidal to columnar epithelium
(sometimes stratified columnar epithelium )
Which duct is the only one able to change the composition of saliva?
Striated Ducts
Which Duct delivers the product the glands produce?
Intercalated Duct
Which duct receives the acinus?
Intercalated Duct
What in saliva starts breaking down fats?
Lipase
Minor (intrinsic) Salivary Glands
- In tongue and lining oral mucosa
2. source of lipase and lysozyme
What can damage Minor Salivary Glands?
Mucoceles
How are Minor Salivary Glands names?
location (labial, buccal, lingual, etc…)
Which Salivary gland goes from lateral border of the face and anterior to the ear?
(Near the ear)
Parotid
Which Salivary gland produces 25% of Saliva ?
Parotid
The Parotid gland excretes via ?
Parotid duct ( Stensen’s Duct)
Parotid papilla
Parotid gland is primarily _____ Secreting
Serous
Which salivary gland is the largest?
Parotid
which salivary gland is affect by mumps?
Parotid
Parotid gland -Serous Acini
Acinar cells contain:
Enzymes ( amylase, Periosidase, Lysosyme)
Antimicrobial Proteins ( cystatins and histatins)
Parotid gland - striated duct
carries products of acini and diluted the saliva via NaCl re absorption
IgA secreted from local plasma cells
Which salivary gland is on the lateral border of the mandible
Submandibular salivary gland
Which salivary gland produces 70% of Saliva ?
Submandibualr
Submandibular Salivary gland secrets via
submandubular duct (Wharton’s Duct)
on booth sides of the lingual frenulum
Submandibular is mostly __________ secretions
Mostly serous but also as some Mucous acini
What duct are in the submandibular gland ?
Striated duct
What produces 5% of Saliva?
Sublingual Salivary Gland
Which salivary gland is below the anterior portion of the tongue?
Sublingual Salivary Gland
Sublingual salivary gland excretes via
- Sublingual ducts (Bartholin’s Duct)
2. Ducts of Rivinus (in multiple locations of the floor of the tongue)
Sublingual salivary gland secretions….
Mostly Mucous acini and some serious acini
Which salivary gland is mostly mucous sections and no capsule ?
Sublingual
Sailvary gland stones
Sailolithiosis
Saliolithiosis causes
calcification of clogged duct
Treatment of Sailolothiosis
Prevention is with hydration
Gland Massage
Sour Lemon Juice to increase Salivary Flow