Histology- Epi and CT Flashcards
What is tissue?
cells that are not identical but come from the same germ layer and carry out similar function/goal
What is Epithelial tissue?
- Create Barriers
- Avascular
- Uninucleated, polyhedral, polarized cells
Connective tissue
Blood, bone, fat, ligaments, cartilage, loose ct, fill empty spaces vasculature and has nerves
Where does epithelial tissue come from?
From all three germ layers
What are the surfaces of epithelial tissue?
Apical
Basal
lateral surfaces
another name for connective tissue
Mucosa and Submucosa
Basement Membrane
Acellular Separation between epithelial and connective tissue
Where do you find epithelial tissue?
- Cover body surfaces
- Line internal cavities
- Present in various organs and glands
- Line ducts
glandular epithelium…
secretes
myoepithelium…
contracts
neuro-epithelium
sensory
Epithelial tissue nomenclature based on
cell layers
cell shape
surface modifications
What are the three primary cell shapes?
Squamous
Cuboidal
Columnar
What kind of cells are these?

Squamous
what cell type is this?

Simple Cuboidal
What cell type is this?

Columnar
what cell type is this?

transitional
Where would transitional cells be found?
when does it change shape?
urinary tract
(Bladder, renal pelvis, ureters)
empty–>squamous
full–>cuboidal
always name tissue based on its
Most superfical layer
The three types of layers are…
Simple
Layered
Pseudistratified
Pseudostratified are usually _____ and are usually found in _______
ciliated and are in the respiratory sytem
Endothelium
Linning of all vasculature
(Simple Squamous)
Mesothelium
Lines body cavity
(Simple Squamous Epithelium)
Epithelial tissue characteristics
- Not protective ( very thin)
- allows absorption and secretion
- controls permeability
Simple Cuboidal Characteristics
- Locations
- Functions
- Glands, Ducts, thyroid and kidney tubules
- secretion and absorption
Simple Columnar Epithelium characteristics
- locations
- functions
- Gut, gallblader, uterine tines, collecting ducts of kidneys
- Protection (thicker), secretion, absorption
Pseudostratified Ciliated Columnar Epithelium
- Locations
- Functions
- Nasal cavity, trachea, brochi, poritons of male reproductive tracts
- Protection, secretion, move mucus with cillia
what is this cell?

Pseudostratified Ciliated Columnar Epithelium
What type of cells are these?

Stratified Squamous Epithelium
Stratified Squamous Epithelium
- Locations
- Functions
- Surface of the skin, linning of mouth, throat, rectum and anus
- Protects against abrasion and pathogens
What type of cell will you find on the surface of the skin, linning of mouth, throat, esophagus, vagina, rectum and anus
stratified squamous epithelium
what type of cells are these ?

Simple columnar epithelium
What type of cells are these?

stratified squamous epothelium
What type of cells are these?

Simple Squamous
What type of cells are these?
what are the white cells?

Simple columnar
(white=goblet cells)
Microvili
- what are they
- Where do you find them?
1.30-fold enhancement of absorption
increase the surface area of cell
- gut and proximal convoluted tubule of the kidney
What are the Luminal surfaces modifications?
- Microvilli
- Stereocilia
- Cillia
Stereocilia
- Elongated (Immovable) Microvilli
- Found in Epididymis, vas deferens, sensory epi of ear
Cilia
- Motile Extension of cell
- Moves fluid and particles
- Dynein, ATPase activity
Dynein
mortor proteins that can propel
Microvilli are made of
actin fillament
Cilia are made of..
Microtubules
(9+2)
Epithelial Cells can be specialized to produce and secrete …
Protein
Mucin
Lipid (Steroid)
Ions and water
Epithelial Cells can be specialized to produce and secrete are controlled under
hormonal/nervous control
How can we can we distinguish the different types of epithelial secretory cells?
change in the organelle content
Gland types
Exocrine and Endocrine
Multicellular Glands
Exocrine
made of more than one cell
Unicellular glands
Exocrine Glands
made one one cell
Unicellular gland example
Goblet Cells
Multicellular Gland Example
(4)
Intestinal Glands
Sweat Glands
Salivary Glands
Mammary Glands
(Exocrine)
Branching or non branched duct portion of multicellular exocrine glands are called ?
Branched duct=compound
non-branched duct =simple
If branches of a multicellular exocrine gland are only in the secretory portion of the gland it will be classified as ?
Simple
Shape of secretory portion of multicellular exocrine glands will be named?
Shape= tubular or Acinar
Complexity= Coiled or Branched
Classify the following glands

Top
Simple Tubular, Simple coiled Tubular, Simple branched tubular
Bottom
Simple Acinar, Simple Branched Acinar
Examples of Simple Tubular Glands
Intestinal Gland
Examples of Simple Coiled Tubular Glands
Merocrine Sweat Glands
Examples of simple branched tubular glands
Gastric glands
Mucous Glands
Esphagus
tongue
duodenum
Examples of Simple Acinar glands
Penile urethra
Example of Simple branched alveolar glands
sebaceous (oil) glands
What are these glands classified as

Left to right
Compound Tubular, Compound Acinar, Compound Tubuloalveolar
Examples of Compound Acinar Glands
Mammary Glands
Examples of Compound tubular glands
Mucous glands
bulbourethral glands
seminiferous tubules
Examples of Compound Tubuloalveolar cells
salivary glands
pancreas
glands of the respiratory passages
All connective tissue comes from which germ layer?
Mesoderm/Mesenchyme
List the Connective Tissue Fibers
Collagen Fibers
Reticulin
Elastic Fibers
Function of Connective tissue
support cells
produce abundant extracellular matrix that seperates cells from one another
Universally Common Extracellular Components (Matrix)
(3)
Connective Tissue FIbers
Ground Substance
Extracellular Fluid
Collagen Fibers are
- Most abundant, flexible and high strength
2.
Collagen Fibers are made of
Collagen fibrils, monomers, called tropocollagen
(triple helix made of 3 intertwined polypeptide chains)
Collagen fibers aa repating pattern
Glycine, hydroxyproline or hydroxylysine, and proline
Type I Collagen
Strongest and most abundant (bones)
Type II Collagen Fibers
Hyaline Cartilage
Type III Collagen
Only one that branches
Type IV and VII Collagen Fibers
Found in the basement membrane
What type of tissue is this?

Collagen Fibers
Reticulin
(3)
- provides supporting framework
- composed of type III collagen
- Branched
(connective tissue fibers)
What is this a picture of?

Reticulin
Elastic Fibers
Allow for response to stretch and distension.
Can Branch
Elastic Fibers are made of
Elastin core and fibrillin microfibrils (thinner than collagen)
Elastic Fibers are made by
fibroblasts and smooth muscle cells
Where can you find elastic fibers?
Arteries
What tissue is this?

Elastic Fibers
What tissue is this?

Elastic Fibers
Ground Substance
- Clear and Viscous
- High water content
- Little morphological structure
What is the function of ground substance?
Diffusion of nutrients and wastes, lubricant, barrier
what is the white portion of this tissue?

ground substance
What is the primary component of Ground Substance?
Proteoglycans
(Large protein core molecules)
What are Proteoglycans?
(Primary component of ground substance)
Protein core surrounded by covalently bound Glycosaminoglycan (GAG) molecules
What is an example of a Proteoglycans ?
Muscin
Connective Tissue Proper Classification
Loose Connective Tissue
Dense Connective Tissue
Irregular
Regular
Specialized Connective Tissue
(6)
Adipose tissue
Cartilage
Bone
Blood
Hematopoietic tissue
Lymphatic tissue
Loose Connective Tissue
Slender bundles of collagen, elastic, watery matrix, fibroblasts, macrophages, mast cells, fat cells
What is this tissue?

Loose connective tissue
Dense connective tissue
- Resistance and protection
- DCT→ fewer cells and a lot of fibers
- Irregular and Regular
What tissue is this?

Dense Regular Connective Tissue
What is this tissue?

Dense Irregular Tissue
Fuctions of Adipose Tissue
Cushions
Insulates
Stores energy and water
Endocrine tissue (adipocytokines)
Adipose Tissue
Dominant cell is the adipocyte (Solitary or clustered)
specialized connective tissue
White Adipose Tissue
Brown Adipose Tissue
White- spherical or polyhedral (highly vascular)
Brown- many blood vessels and Mitochondria,Polygonal
What is this tissue?

White Adipose Tissue
What tissue is this?

Brown Adipose Tissue