Saliva Flashcards

1
Q

What much saliva do we produce day and night

A

1-1.5 litres during day
10ml at night

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2
Q

Composition of saliva

A

Water 99%
Organic and inorganic substance 1%

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3
Q

Why is whole/mixed saliva found in oral cavity different to pure saliva produced in the glands

A

Gingival crevicular fluid secreted from inflamed gingival pockets is part of whole saliva when periodontal disease is present.
Along with food, epithelial cells and bacteria.

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4
Q

What is the resting range pH of saliva

A

6.7-7.4

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5
Q

What can vary the pH of saliva

A

Time of day
What has been eaten

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6
Q

Those with a lower pH tend to…

A

Get more caries

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7
Q

Those with a higher pH tend to…

A

Produce more calculus

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8
Q

What are the main organic components found in saliva

A
  • Proteins; mucin and enzymes
  • Immunoglobulins
  • Waste products
  • Cells
  • Food debris
  • Hormones
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9
Q

What properties do many proteins in the saliva possess?

A

Antibacterial

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10
Q

Agglutination

A

Immunoglobulins aid in disposal of bacteria by clumping them together and making them unable to cling to oral cavity surfaces.
Works with serous saliva.

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11
Q

What component gives saliva a sticky/viscous consistency?

A

Mucin

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12
Q

2 types of mucin proteins

A

Muco-proteins
Glyco-proteins

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13
Q

By products of cell metabolism found in saliva

A

Urea; can neutralise acid
Uric acid
Ammonia; raises pH

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14
Q

What cell products are found in saliva

A

Worn out/dead epithelial cells
White blood cells (leukocytes in gingival crevicular fluid)
Commensal bacterial cells (do not harm human health)

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15
Q

What hormones are present in saliva?

A

Oestrogen and progesterone

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16
Q

Main inorganic components found in saliva

A

Ions (mineral salts)
Gas

17
Q

Main function of ions in saliva

A

Buffering effect to try maintain neutral pH levels

18
Q

What ion plays a major role in caries and calculus formation

A

Calcium phosphate

19
Q

Gas components found in saliva

A

Oxygen
Nitrogen
Carbon dioxide

20
Q

Main functions of saliva

A

Protection
Buffering
Digestion
Taste
Antimicrobial
Tooth integrity

21
Q

How does saliva protect

A

Glyco proteins lubricate soft tissues this helps to;
- protect from abrasion
- aid speech
- maintain healthy mucosa
- cleansing effect
- form salivary pellicle

22
Q

What proteins aids with the breakdown of food and forming bolus

A

Salivary amylase

23
Q

How does saliva impact taste

A

Taste sensation can only be detected when substances are in a solution

24
Q

What are patients with xerostomia at increased risk of?

A

Deposition of plaque
Caries
Periodontal disease

25
How does saliva aid with tooth integrity
Ions in saliva act as a fluoride reservoir and aid in maturation of enamel in newly erupted teeth and repair from acid attacks.
26
Main ways saliva protects against caries?
- first layer of salivary pellicle protects against acid - inorganic ions buffering pH to help maintain neutral - serous saliva and its cleansing effect
27
Ionic see-saw
Although the saliva buffering system can reduce extent of pH fall, during prolonged sugar attacks in the mouth this can exhaust the buffering system to contain ion removal.
28
What stimulates salivation
Sensory inputs; Sight Smell Taste
29
What nerves supply the saliva glands and control salivation
Sympathetic Parasympathetic
30
Role of sympathetic stimulation in salivation
Reduces saliva flow due to vasoconstriction. (Stressful situations)
31
Role of parasympathetic stimulation during salivation
Increases salivary flow due to vasodilation. (Relaxed)
32
Factors that may cause increase saliva flow
Mastication Gingival conditions Hunger Smell/sight of food Teething in babies
33
Factors that may decrease saliva flow
Diabetes Alcohol Drugs Fear Radiotherapy Surgery
34
Medical conditions that can impact saliva flow
Parkinson’s Diabetes HIV/AIDS Sjögren’s syndrome Radiation/chemotherapy Saliva gland disorders