Role of Brain Structures in Mood Disorders Flashcards
Hippocampus Normal function
short term memory
Hippocampus and mood disorders
Depressed pts can’t access short term memory
Manic pts can’t access sad memories
Thalamus normal function
Regulates emotion, motivation, arousal, and attention
Thalamus in mood disorders
Loss of pleasurable responses to sensation in depression. Sometimes associated with hypersensitivity to sensory input in mania
Dorsolateral Prefrontal cortex in normal function
conscious thought, executive functions
Dorsolateral prefrontal cortex in mood disorder
helplessness, indecisiveness, distorted sense of time– Slowed in depression and accelerated in mania
Orbitofrontal cortex
asses risk in pursuit of reward, relate new info to context.
Orbitofrontal cortex in mood disorder
overestimates risk in depression, underestimates it in mania
Nucleus acumbens
Reward…..pretty easy, lack of reward in depression, excess reward in mania
Anterior Cingulate gyrus
Integration of emotion and cognition
Amygdala
fear, rage, selective attention