Rocuronium bromide

Question 1

List the indications for rocuronium bromide (Zemuron).

Answer 1

• MFI after administration of sedation/analgesia (When succinylcholine is contraindicated and sedation/analgesia is not enough to facilitate intubation and rescue airway available with no contraindications to use of the rescue airway)
• Post intubation to facilitate airway control & maintain muscle paralysis

Question 2

What is the MFI Loading dose for rocuronium bromide?

Answer 2

0.6 to 1.2 mg/kg IVP (in most patients intubation can proceed within 2 min; Use patient’s total body weight)

Question 3

What is the maintenance dose for rocuronium bromide?

Answer 3

0.1 to 0.6 mg/kg IVP; Use patient’s total body weight

Question 4

List the contraindications for rocuronium bromide.

Answer 4

• Hypersensitivity to drug or components
• A difficult intubation in a patient who is presently self ventilating adequately and ventilation may be difficult once paralyzed

Question 5

Your patient is taking an acetylcholinesterase inhibitor, what affect could this have on rocuronium bromide?

Answer 5

Acetylcholinesterase inhibitors, such as neostigmine, antagonize the action of rocuronium.