Octreotide

Question 1

Indications for Octreotide administration

Answer 1

1. Emergency management of bleeding esophageal varices in patient with liver cirrhosis and for protection against re-bleeding
2. Hypoglycemia secondary to oral hypoglycemic poisoning

Question 2

Dosages for Octreotide admin (2)

Answer 2

Oral hypoglycemic OD refractory to dextrose:
Adult: 100 mcg IV/IO/SC q 6 hours prn
Peds: 2 mcg/kg/IV/IO/SC Q 6 hours prn

Upper GI bleed:
50 mcg IV/IO SIVP, then start infusion at 50 mcg/hr. Mix 500 mcg into a 250 mL NS which results in a concentration of 2 mcg/mL

Question 3

Contraindications for Octreotide

Answer 3

Hypersensitivity