Phenytoin

Question 1

Indications for the use of phenytoin

Answer 1

Status epilepticus refractory to benzodiazepines

Question 2

Dosage for phenytoin (Dilantin)

Answer 2

Seizures: 15-20 mg/kg IV infusion with NS dilute to a maximum concentration of 10mg/ml (*do not exceed 50 mg/min.)

Question 3

How long should an IV infusion of phenytoin (Dilantin) be given over?

Answer 3

75kg or less: over at least 30 min
76kg to 150kg: over at least 60 min
151kg or greater: over at least 90 min

Question 4

Contraindications - phenytoin (Dilantin)

Answer 4

❑ Hypersensitivity
❑ Bradycardia
❑ High grade heart block ex. 2nd and 3rd, Adam Stokes Syndrome
❑ Concurrent toxic ingestion (e.g., TCA, cocaine, etc.)

Question 5

What must you use when administering phenytoin IV?

Answer 5

Must run through micro filter.