Mannitol

Question 1

Indications for the use of Mannitol

Answer 1

To reduce intracranial pressure or cerebral edema associated with head injury trauma and stroke with GCS of < 8 and one or more of abnormal pupils or abnormal motor exam (i.e. posturing).

Question 2

Dosage for Mannitol

Answer 2

Adult/Pediatric: 0.5-1.0 g/kg IV infusion over 15 min.; May repeat 0.25-2.0 g/kg over 30 min. q 4 hours

Question 3

Contraindications to Mannitol use

Answer 3

❑ CHF, pulmonary edema
❑ Severe dehydration or electrolyte depletion
❑ anuria

Question 4

What must always be used when administering Mannitol?

Answer 4

It must always be administered through a micron filter as it is prone to crystallization.