RNA viruses

Question 1

what kind of genetic material is in the reovirus?

Answer 1

DS linear RNA

Question 2

is the reovirus positive or negative sense?

Answer 2

positive

Question 3

is the reovirus segmented?

Answer 3

yes, 10-12 segments

Question 4

is the reovirus enveloped?

Answer 4

no

Question 5

what kind of genetic material is in a picornavirus?

Answer 5

ss linear RNA

Question 6

is the picornavirus negative or positive sense?

Answer 6

positive

Question 7

is the picornavirus enveloped?

Answer 7

no

Question 8

poliovirus is a member of

Answer 8

picornavirus

Question 9

rhinovirus is a member of

Answer 9

picornavirus

Question 10

what kind of genetic material is in favivirus

Answer 10

ss linear RNA

Question 11

are faviviruses enveloped?

Answer 11

yes

Question 12

are flaviviruses positive or negative sense?

Answer 12

positive

Question 13

faviviruses are caused by

Answer 13

zoonotic spread

Question 14

what type of genetic material is in orthomyxovirus?

Answer 14

• sense ss linear RNA

Question 15

where do orthomyxoviruses replicate?

Answer 15

nucleus

Question 16

how many segments do orthomyxoviruses have?

Answer 16

8

Question 17

are orthomyxoviruses enveloped?

Answer 17

yes

Question 18

what kind of capsid do orthomyxoviruses have?

Answer 18

helical

Question 19

hemagglutinin binds to

Answer 19

sialic acid receptors on host cell to promote viral entry

Question 20

influenza is caused by

Answer 20

orthomyxoviruses

Question 21

antigenic shift

Answer 21

reassortment of entire genome, shift in phenotype

Question 22

antigenic shift causes

Answer 22

pandemics

Question 23

antigenic drift

Answer 23

point mutations

Question 24

antigenic drift causes

Answer 24

epidemics

Question 25

neuraminidase promotes

Answer 25

viral progeny release

Question 26

classic influenza presentation

Answer 26

fever, cough, sore throat, myalgia

Question 27

oseltamivir, zanamivir

Answer 27

NA inhibitors

Question 28

oseltamivir, zanamivir treat which strain of the flu

Answer 28

A and B

Question 29

amantidine

Answer 29

impairs viral uncoating

Question 30

amantidine is used against what flu strain

Answer 30

A

Question 31

paramyxoviruses have what genetic material

Answer 31

-sense ss linear RNA

Question 32

are paramyxoviruses enveloped?

Answer 32

yes

Question 33

are paramyxoviruses segmented?

Answer 33

no

Question 34

virulence factors: paramyxoviruses

Answer 34

HA NA matrix protein F protein

Question 35

pavlizimuab

Answer 35

RSV PPX in premature infants

Question 36

RSV causes ____ in infants

Answer 36

bronchiolitis

Question 37

croup is caused by

Answer 37

parainfluenza virus

Question 38

laryngotracheobronchitis

Answer 38

croup

Question 39

barking seal like cough and inspiratory stridor

Answer 39

croup

Question 40

steeple sign

Answer 40

croup

Question 41

prodromal fever with cough, coryza, conjunctivitis, koplik spots

Answer 41

measles

Question 42

koplik spots

Answer 42

bright red spots with blue white center on buccal mucosa

Question 43

maculopapular rash that starts at the head/neck and spreads down

Answer 43

measles

Question 44

Warthin-Finkeldey giant cells

Answer 44

measles

Question 45

non-specific prodrome (fever, malaise, headaches, myalgias)

Answer 45

mumps

Question 46

parotitis, orchitis

Answer 46

mumps

Question 47

aseptic meningitis

Answer 47

mumps

Question 48

what genetic material is in rhabdoviruses?

Answer 48

- sense ss linear RNA

Question 49

are rhabdoviruses enveloped?

Answer 49

yes

Question 50

are filoviruses enveloped?

Answer 50

yes

Question 51

what kind of capsid do filoviruses have?

Answer 51

helical

Question 52

what kind of genetic material to filoviruses have

Answer 52

-sense linear ssRNA

Question 53

what kind of genetic material do arenaviruses have?

Answer 53

+ and - sense circular ssRNA 2 segments

Question 54

what kind of capsid do arenaviruses have?

Answer 54

helical

Question 55

what kind of genetic material is in bunyaviruses?

Answer 55

-sense circular ssRNA 3 segments

Question 56

is bunyavirus enveloped?

Answer 56

yes

Question 57

what kind of capsule does bunyavirus have?

Answer 57

helical