-RNA enveloped (Hanta, Lassa, Rabies, Ebola)

Question 1

what virus are found in the bunya family?

Answer 1

La Cross

California encephalitis

Hanta virus

Question 2

what viruses are found in the Arena virus family?

Answer 2

Lassa

LCMV

Question 3

what viruses are found in the Rhabdo virus family?

Answer 3

rabies

Question 4

what viruses are found in the filo family of viruses?

Answer 4

Ebola

Question 5

what is the transmission of La Cross and California Encephalitis?

Answer 5

from squirrel to mosquito which will pass it to humans

Question 6

what is the transmission of Hantavirus?

Answer 6

aerosolized mice urine

Question 7

what is the transmission of Lassa virus?

Answer 7

through mice urine

Question 8

what is the transmission of LCMV?

Answer 8

through mice urine

Question 9

what is the transmission of rabies?

Answer 9

through saliva of mammals

Question 10

what is the transmission of ebola?

Answer 10

humans and primates transmit it

among humans, infection occurs by body fluids

Question 11

what is the clinical presentation of La Cross encephalitis?

Answer 11

fever, headache, vomiting, meningitis

Question 12

what is the clinical presentation of california encephalitis virus?

Answer 12

fever, headache, vomiting, encephalitis

Question 13

what is the clinical presentation of Hantavirus?

Answer 13

Hanta Pulmonary Syndrome:

• flu-like symptoms
• pulmonary edema
• respiratory failure

Hemorrhagic Fever with renal syndrome (kidney necrosis, external bleeding)​

Question 14

where is Lassa virus found?

Answer 14

West Africa

Question 15

what is the clinical presentation for Lassa virus?

Answer 15

Lassa fever (high fever, bleeding gyms and blood vomiting, liver/spleen necrosis)

Question 16

LCMV (lymphocytic choriomeningitis virus) will infect what mice?

Answer 16

house mice

Question 17

what is the clinical presentation of LCMV?

Answer 17

fever, flu-like myalgia

Question 18

what is the biology of the rabies virus?

Answer 18

eveloped BULLET SHAPED helical single stranded -RNA

Question 19

to what receptor will the VAP of rabies virus attach to?

Answer 19

nicotinic ACh receptor

Question 20

What animal is most prone to infect with rabies?

Answer 20

raccoons and skunks

Question 21

what happens with rabies once someone is infected?

Answer 21

virus can travel to CNS and to salivary glands

Question 22

what is the clinical presentation of rabies during incubation?

Answer 22

flu-like symptoms

Question 23

what is the clinical presentation of rabies after incubation?

Answer 23

neurological phase:

• itching at site of bite
• cerebral dysfunction
• deliruim
• hydrophobia

Question 24

what is the prognosis of rabies once clinical signs appear?

Answer 24

disease is fatal

Question 25

what diagnosis tool can be used to confirm rabies?

what cytoplasmic inclusions can be found?

Answer 25

antibodies in the CSF

Negri bodies

Question 26

what cytoplasmic inclusion is this?

Answer 26

negri body

Question 27

what cytoplasmic inclusion is this?

Answer 27

negri bodies

Question 28

what rabies vaccine is given before exposure to rabies virus?

Answer 28

killed vaccine

Question 29

what rabies vaccine is given after exposure to rabies virus?

what happens if you acquire the virus, when do you give the vaccine?

Answer 29

killed vaccine

human rabies immune globulin

when you acquire the virus, you must administer both vaccines before onset of symptoms

Question 30

what is the clinical presentation of ebola?

Answer 30

extensive hemorrhage from GI and hypovolemic shock

and vomiting