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Microbiology Block 1 > +RNA enveloped (corona, Rubella, Toga, Flavi, Arboviruses) > Flashcards

+RNA enveloped (corona, Rubella, Toga, Flavi, Arboviruses) Flashcards

1
Q

what is the second most common cause of the common cold?

A

corona viruses

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2
Q

corona virus are responsible for these 2 disease?

A

1) SARS
2) MERS

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3
Q

what is the clinical presentation of coronavirus?

A

upper respiratory tract infection

*no fever, cough, sore throat

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4
Q

what cells does coronavirus infect primarily?

A

epithelial cells of the upper respiratory tract

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5
Q

SARS is usually limited to a travel history of what?

A

toronto and far eash china

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6
Q

what is the clinical presentation of SARS?

A

atypical pneumonia

fever

dyspnea and progressive hypoxia

diarrhea

Chest X ray shows patchy distribution of focal interstitial infiltrates

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7
Q

what is another name for rubella?

A

3 day measles

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8
Q

what is the biology of rubella?

A

envelped ss+RNA

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9
Q

what cells will rubella infect?

A

respiratory cells

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10
Q

what is the progression of infection?

A

1) it infects upper respiratory tract and spreads to lymph nodes
2) viremia and spread to whole body

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11
Q

why does the rubella virus spread?

A

because of unvaccination

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12
Q
A
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13
Q

what is the clinical presentation for rubella?

A

fever

coryza (runny nose)

conjunctiva (red eyes)

cough

erythematous maculo-papular rash

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14
Q

when does the rubella rash disappear?

A

72 hours

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15
Q

how does the erythematous maculo papular rash in rubella appear?

A

first on face and spreads to trunk

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16
Q

how is rubella prevented?

A

through vaccine = MMR

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17
Q

what causes this? what is this?

A

rubella, erythematous maculo papular rash

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18
Q

what can be a complication that can happen with rubella?

A

congenita rubella syndrome

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19
Q

what is congenital rubella syndrome?

A

rubella virus crosses placenta when “sero-negative”mother has primary infection.

20
Q

what determines the seriousness of congenital rubella syndrome?

A

the time period of infection

21
Q

what are some of the symptoms seen in congenital rubella syndrome?

A

thrombocytopenic purpura (blu-berry muffin baby)

microcephaly

mental retardation

cataracts

22
Q

what confirms a diagnosis of rubella?

A

presense of anti-rubella IgM or IgG

23
Q

what is the biology of Togavirus?

A

enveloped ss+RNA

24
Q

what are the 2 families of togavirus?

A

1) Arbovirus
2) Rubivirus

25
Q

how are togavirus transmitted?

A

mosquitoes

26
Q

what are the 3 viruses in togavirus?

A

1) EEE, WEE, VEE
2) Chikagunya
3) West Nile

27
Q

what symptom will EEE, WEE, VEE cause?

A

encephalitis

28
Q

what symptom will chikugunya cause?

A

joint pain and rash

29
Q

what symptom is seen in west nile virus?

A

encephalitis

30
Q

what mosquito causes EEE, WEE, VEE?

31
Q

what mosquito causes chikugunya?

32
Q

what mosquito causes west nile?

33
Q

what is the biology of flavivirus?

A

it is enveloped single stranded +RNA

34
Q

how is flavivirus transmitted?

A

mosquitoes (arthropod borne) and if transfusion of infected blood or transplantation

35
Q

what is the treatment for yellow fever?

36
Q

when is arbovirus mostly affecting patients? (when are patients mostly going to be seen with this?)

37
Q

what is the host for arbovirus? what is important about this?

A

humans, they are dead end host (once infect human it cannot further spread)

38
Q

what is the incubation period for EEE (eastern equine encephilitis), WEE (western equine encephilitis), VEE (venezuelan equine encephilitis)?

39
Q

what is the clinical presentation for EEE, WEE, VEE?

A

fever

headache

vomiting

Tremors

convulsions

disorientation

40
Q

how is EEE, WEE, VEE different from herpes simplex virus?

A

there are no flu-like symptom preceding the symptoms

41
Q

how is the recovery for EEE, WEE, VEE?

A

complete when there is no central nervous system involvement.

42
Q

what is the clinical presentation for flavivirus?

A

tremor

convulsions

spastic paralysis

43
Q

what is the clinical presentation for dengue 1st time infection?

A

fever

severe joint pain (1 week duration)

44
Q

what is the clinical presentatin for dengue haemorragic fever?

A

fever

hemorrhagic manifestations

thrombocytopenia

leaky capillaries

muscle and bone pain

45
Q

what is the clinical presentation for Dengue Haemorrhagic Shock Syndrome?

A

fever

hemorrhagic manifestations

thrombocytopenia

leaky capillaries

muscle and bone pain

shock

46
Q

what is the clinical presentation of yellow fever?

A

Severe high fever,

jaundice,

GI bleeding (GI) “Black vomit”,

shock

failure of multiple organs.

47
Q

how is yellow fever prevented?

A

Attenuated Live-virus vaccine

Microbiology Block 1 (16 decks)

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