RISK FACTORS, CAUSALITY, BRADFORD HILL CRITERIA Flashcards
when was bradford hill criteria made
1965
what is bradford hill
Widely recognised as a basis for causality assessment in epidemiology
In order to say that an association is causal, it should meet as many from this criteria as possible:
1) Strength of the association
2) consistentecy
3)Specificity of the association
4) temporlaity
5) Biological gradient
6) plausible
7) coherance
8) experiment
9) analogy
most common risk measures
1) RR
2) attributable risk
3) ODDS
WHAT would make something a protective factor
if the RR <1
define Relative risk
help you remember you are dividing
A ratio of the incidence in the exposed group (IE) compared to the incidence in the unexposed group (INE) ∴ IE/INE
e.g smoking in causing cancer for example
attributable risk
help you remember you are taking away
the difference between the incidence in the exposed group and the incidence in unexposed group ∴IE – INE
odds ratio
the relationship pf the probability of occurrence of an event to that of non- occurrence.
what gives you A snapshot of disease distribution in a population at a given moment.
incidence
difference bbetwen incidence and prevelence
time interval in incidence you need to have a time interval
Methods for studying incidence
Sources:
Data from the patient and his/her family
Data from medical establishments
Data from death registries
morbity
any departure, subjective or objective from a state of physiological wellbeing. Usually accept as a statistical concept including all cases of diseases that the health system is informed about.
“Epidemic situation
Low level of health prevention and treatment”
what does this mean
high incidence and high prevelence
which group does an aged popuplaution fall under
low incidence + high prevelence
confounding variable
A confounding variable is a third variable that influences both the independent and dependent variables.
it has to affect both
e.g alchol and heart disease
but smking is a confounding variable as it affects both
definition of risk
Generally, risk refers to the probability that an event will
occur. In epidemiology, risk refers to the probability that
person, exposed to certain factors (risk factors) will
subsequently develop a particular disease.