Risk Analysis in Toxicology Flashcards
For risk to be present, there must be two things. What are they?
- Exposure
2. A consequence arising out of exposure (adverse effect)
Risk assessment adheres to a 4-step process. What are those 4 steps?
- Problem formulation
- Effects characterization
- Exposure characterization
- Risk characterization
If you were given exposure and effect, how would you calculate risk?
Effect / exposure
True or False: Dose = exposure.
TRUE
True or False: Toxicity = risk.
FALSE: toxicity = effect
What does this define: the likelihood of harm to be manifested under relevant conditions of exposure?
Risk
What does this define: systematic scientific evaluation of potential adverse effects from exposures to hazardous agents or situations?
Risk assessment
What does this define: intrinsic toxic properties?
Hazard
What does this define: process by which policy actions are chosen to address and mitigate risk?
Risk management
What does this define: making risk assessment outcomes and risk management decisions comprehensible to interested and affected parties?
Risk communication
What does this define: the interrelated activities of risk assessment, management, communication, and perception?
Risk analysis
What is risk in relation to exposure and effect?
Risk is the joint probability of exposure and effect = f(exposure, effect)
Which part of the risk assessment process is the toxicology and biology?
Effects characterization
Which part of the risk assessment process involves source, route, duration, and intensity?
Exposure characterization
Which part of the risk assessment process is the confluence of exposure and effect?
Risk characterization
