Recreational Drugs Flashcards

1
Q

What are the clinical effects of amphetamine?

A
  1. Dilated pupils
  2. CNS stimulation (tremors, seizures)
  3. Hyperthermia due to the tremors
  4. Tachycardia
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2
Q

How would one treat amphetamine toxicity?

A
  1. Emetics, AC, cathartics
  2. Urine acidifiers (ascorbic acid)
  3. Sedatives (diazepam) for seizures
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3
Q

Is mariguana a CNS stimulant or CNS depressant?

A

CNS depressant

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4
Q

How is marijuana excreted from the body?

A

Via bile

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5
Q

Marijuana is metabolized by liver _____ and _____.

A

Hydroxylation and oxidation

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6
Q

What is the most active cannabinoidal agent in marijuana?

A

Delta-9-THC

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7
Q

Is marijuana lipophilic or lipophobic?

A

Lipophilic

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8
Q

Marijuana has a long half-life in which part of the body?

A

Adipose tissue

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9
Q

True or False: Plasma is a good sample to take to diagnose marijuana intoxication.

A

FALSE: Marijuana has a short half-life in plasma

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10
Q

Marijuana acts on receptors in the brain selective for what?

A

Cannabinoids

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11
Q

The action of marijuana on brain receptors selective for cannabinoids causes the release of what?

A
  1. Norepinephrine
  2. Dopamine
  3. Serotonin
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12
Q

Marijuana also interacts with acetylcholine, _____, opioid peptides, and _____.

A
  1. Histamines

2. Prostaglandins

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13
Q

What are the clinical effects associated with marijuana?

A
  1. Euphoria –> depression
  2. Vomiting
  3. Dilated pupils
  4. Nystagmus
  5. Coma
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14
Q

With a marijuana ingestion, what extra clinical sign might horses present with?

A

Colic

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15
Q

What is the time of onset for clinical signs associated with marijuana?

A

30-90 minutes

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16
Q

What is the length of duration of clinical signs associated with marijuana?

A

Up to 72 hours

17
Q

How might one treat a marijuana ingestion?

A
  1. Emetics, AC, cathartics
  2. Doxapram to stimulate respiration
  3. Respiratory support
18
Q

What are the samples you might choose to use to diagnose marijuana intoxication?

A
  1. Urine

2. Stomach contents

19
Q

What is an alkaloid derivative of the coca plant?

20
Q

What does “crack-cocaine” refer to?

A

The pure form of the drug

21
Q

Does cocaine have a long or short half life?

A

Short half life

22
Q

Is cocaine rapidly or slowly absorbed?

23
Q

Is cocaine a CNS stimulant or CNS depressant?

A

CNS stimulant

24
Q

What are the clinical effects of cocaine?

A
  1. Cardiotoxicity
  2. Dilated pupils
  3. Tachycardia
  4. Depression/coma
  5. Seizures
25
What clinical signs are associated with HIGH DOSES of cocaine?
1. Ptyalism 2. Fever 3. Seizures 4. Hypoglycemia 5. Hyperthermia 6. Hypertension 7. Hyperesthesia 8. Tachycardia
26
How might one treat a cocaine intoxication?
1. Emetics, AC, cathartics 2. Control seizures (diazepam) 3. Respiratory supoort 4. Control arrhythmias (propanolol) 5. Control hyperthermia
27
What 3 samples might you take to diagnose a cocaine intoxication?
1. Urine 2. Plasma 3. Stomach content
28
What are the clinical effects of narcotics (opioid derivatives such as codeine, morphine, fentanyl, and heroine) in dogs?
1. Ataxia 2. Vomiting 3. Hypotension 4. Respiratory depression 5. Seizures 6. Miosis 7. Coma
29
What are the clinical effects of narcotics (opioid derivatives such as codeine, morphine, fentanyl, and heroine) in cats and horses?
CNS excitation
30
How might one treat a narcotic intoxication, say in a dog?
1. Emetics, AC, cathartics 2. Respiratory support 3. Naloxone 4. Supportive care (fluid, seizure control)
31
In what samples might you detect narcotics for diagnosis?
1. Urine | 2. Serum
32
What are the clinical effects of ethanol?
1. Emesis 2. Respiratory depression 3. Respiratory and cardiac arrest 4. Ataxia/in-coordination 5. Excitability/vocalization
33
How might one treat an ethanol intoxication?
1. Emetics, AC, cathartics 2. Maintain ventilation 3. Monitor acid-base, electrolyte, fluid balance 4. Maintain body temp
34
What are the clinical pathologic effects of xylitol?
1. Hyperbilirubinemia 2. Hypoglycemia 3. Hyperphosphatemia 4. Increased clotting times
35
What 2 systems does xylitol effect?
1. Hepatic | 2. GI