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Sem 3: BacT > Rickettsia - Muller > Flashcards

Rickettsia - Muller Flashcards

1
Q

Rickettsia: Gram + or Gram -?

A

Gram neg

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2
Q

What stain should be used for Rickettsia?

A

Giemsa / Diff Quick

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3
Q

True or False: Rickettsia are obligate intracellular bacteria

A

TRUE

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4
Q

Why are rickettsia spp. hard to culture?

A

Bc obligate intracelluar bacteria

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5
Q

How can humans, dogs, and other animals be infected with rickettsia?

A

Through arthropod bite or arthropod feces inoculation/inhalation

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6
Q

What is the vector for RMSF?

A

Ticks - Dermacentor, Amblyomma, Rhipicephalus

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7
Q

What are the clinical signs of RMSF?

A

Skin maculopapular rash in humans

Fever, SQ edema, petechia in mucosa, myalgia

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8
Q

R.felis causes what CS in cats?

A

None, asymptomatic

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9
Q

what rickettsia spp. causes murine typhus?

A

R. typhi

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10
Q

What is the vector for r. typhi?

A

C. felis and Xenopylla

  • cat flea and rodent flea
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11
Q

What are the CS of r.typhi in humans?

A

Eschar (lesion on skin)

  • Lymphadenomegaly
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12
Q

How are rickettsial diseases treated?

A

Tetracycline, Doxy, Chloramphenicol, Enrofloxacin

**Antibiotics that target intracellular bacT

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13
Q

What is the best way to diagnose rickettsia in humans and dogs?

A

Serology

**not PCR bc incidental hosts have low rickettsemia

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14
Q

Culture and isolation os rickettsia requires a BSL __ lab

A

BSL3

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15
Q

When would you want to use PCR to diagnose rickettsia?

A

useful in reservoirs and vectors

Ex: opossum, cats, rats, fleas, ticks

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16
Q

Anaplasma phagocytophilum infects what cell type?

A

Neutrophils and maybe eosinophils

17
Q

What are the reservoirs for anaplasma phagocytophilum?

A

small mammals and deer

18
Q

What is the vector for anaplasma phagocytophilum?

A

ixodes ticks

19
Q

What CS are seen in humans and dogs with granulocytic anaplasmosis?

A

Musculoskeletal pain, headache, fever, lethargy

**Have to differentiate from Lyme disease which has similar CS

20
Q

Canine cyclic thrombocytopenia is caused by what disease?

A

Anaplasma platys

21
Q

What is the vector that transmits anaplasma platys?

A

Tick - Rhipicephalus sanguineus

22
Q

Bovine anaplasmosis is caused by?

A

Anaplasma marginale

23
Q

Which disease has a high mortality in naive adult cattle and is more resistant in young calves?

A

Anaplasma marginale

24
Q

How can you treat bovine anaplasmosis?

A

Long-acting oxytetracycline

25
Q

Why is Ehrlichia canis prevelant in st kitts?

A

Bc ticks are abundant in warm season and its always warm here

26
Q
A

Sem 3: BacT (16 decks)

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