Rickettsia - Muller Flashcards
Rickettsia: Gram + or Gram -?
Gram neg
What stain should be used for Rickettsia?
Giemsa / Diff Quick
True or False: Rickettsia are obligate intracellular bacteria
TRUE
Why are rickettsia spp. hard to culture?
Bc obligate intracelluar bacteria
How can humans, dogs, and other animals be infected with rickettsia?
Through arthropod bite or arthropod feces inoculation/inhalation
What is the vector for RMSF?
Ticks - Dermacentor, Amblyomma, Rhipicephalus
What are the clinical signs of RMSF?
Skin maculopapular rash in humans
Fever, SQ edema, petechia in mucosa, myalgia
R.felis causes what CS in cats?
None, asymptomatic
what rickettsia spp. causes murine typhus?
R. typhi
What is the vector for r. typhi?
C. felis and Xenopylla
- cat flea and rodent flea
What are the CS of r.typhi in humans?
Eschar (lesion on skin)
- Lymphadenomegaly
How are rickettsial diseases treated?
Tetracycline, Doxy, Chloramphenicol, Enrofloxacin
**Antibiotics that target intracellular bacT
What is the best way to diagnose rickettsia in humans and dogs?
Serology
**not PCR bc incidental hosts have low rickettsemia
Culture and isolation os rickettsia requires a BSL __ lab
BSL3
When would you want to use PCR to diagnose rickettsia?
useful in reservoirs and vectors
Ex: opossum, cats, rats, fleas, ticks
Anaplasma phagocytophilum infects what cell type?
Neutrophils and maybe eosinophils
What are the reservoirs for anaplasma phagocytophilum?
small mammals and deer
What is the vector for anaplasma phagocytophilum?
ixodes ticks
What CS are seen in humans and dogs with granulocytic anaplasmosis?
Musculoskeletal pain, headache, fever, lethargy
**Have to differentiate from Lyme disease which has similar CS
Canine cyclic thrombocytopenia is caused by what disease?
Anaplasma platys
What is the vector that transmits anaplasma platys?
Tick - Rhipicephalus sanguineus
Bovine anaplasmosis is caused by?
Anaplasma marginale
Which disease has a high mortality in naive adult cattle and is more resistant in young calves?
Anaplasma marginale
How can you treat bovine anaplasmosis?
Long-acting oxytetracycline
Why is Ehrlichia canis prevelant in st kitts?
Bc ticks are abundant in warm season and its always warm here
