Actinobacillus spp - Gutierrez Flashcards

1
Q

Actinobacillus is in the ________ family

A

Pasteurellaceae

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2
Q

Culture of actinobacillus should be done on _________

A

MacConkey

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3
Q

Which is not true about Actinobacillus spp?
A. Fastidious
B. Grows on MacConkey
C. Infects a wide range of hosts
D. Some are NAD dependent
E. Has a capsule

A

C. Infects a wide range of hosts

FALSE: notable host restriction

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4
Q

What actinobacillus spp are of veterinary importance?

A
  1. A. pleuropneumoniae
  2. A. suis
  3. A. equuli
  4. A. lignieresii
  5. A. seminis
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5
Q

Actinobacillus seminis infects what species?

A

Sheep and goats

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6
Q

Actinobacillus equuli infects what species?

A

Horses and pigs

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7
Q

Actinobacillus lignieresii infects what species?

A

Bovine

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8
Q

Actinobacillus pleuropneumoniae infects what species?

A

Pigs

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9
Q

True or False: Actinobacillus spp forms biofilms which protect it from hostile environments

A

TRUE

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10
Q

________ plays a role in adhesion of actinobacillus spp

A

LPS

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11
Q

Secretion of ______ group of toxins are hemolytic and leukocytic

A

RTX

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12
Q

What is the predisposing factor for infection of actinobacillus?

A

Viral infections, trauma, stress, low maternal immunity

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13
Q

________ is the only actinobacillus spp that is considered a primary pathogen

A

Actinobacillus pleuropneumoniae

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14
Q

Actinobacillus pleuropneumoniae colonizes in the __________

A

URT of healthy pigs only

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15
Q

Reservoir of Actinobacillus pleuropneumoniae?

A

Tonsils of pigs

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16
Q

Which form of Actinobacillus pleuropneumoniae results in high morbidity and mortality?

A

Peracute / acute form

17
Q

Main toxins involved in the pathogenesis of Actinobacillus pleuropneumoniae?

A

ApxI - most potent. hemolytic and leukocytic

  1. ApxII - less potent. hemolytic and leukocytic
  2. ApxIII - potent but not hemolytic
18
Q

Actinobacillus suis colonizes in _________

A

URT and vagina of healthy pigs

19
Q

Actinobacillus equuli subsp. equuli is known as _________

A

Sleepy foal disease

20
Q

The chronic form of Actinobacillus equuli subsp. equuli is characterized by __________

A
  1. Purulent arthritis (joint ill)
  2. Suppurative multifocal nephritis
21
Q

What actinobacillus equuli spp infects only horses?

A

Actinobacillus equuli subsp. haemolyticus

22
Q

__________ actinobacillus spp causes wooden (timber) tongue

A

A. lignieresi

23
Q

Disease development of actinobacillus lignieresi occurs after ___________

A

Inoculation into mucous membranes during abrasion by rough feed

24
Q

Pyogranulomatous lesions formed by actinobacillus lignieresi resemble those of ___________

A

Actinomyces bovis

25
Q

Which is not true of actinobacillus lignieresi?
A. Bone is usually unaffected
B. Facultative aerobe
C. Spreads via lymphatics
D. Abscesses can be seen on the jaw, head, neck, and limbs

A

B. Facultative aerobe

FALSE: Facultative anaerobe

26
Q

What can be seen on growth of actinobacillus spp on sheep blood agar?

A

Satellitism (NAD dependence = staphylococcus required for growth) and CAMP effect (Co-hemolysin)

27
Q

What vaccines are available for actinobacillus?

A
  1. Bacterins
  2. Apx toxins
  3. Apx + Transferrin binding proteins
  4. Apx + TBP + Type IV fimbriae
28
Q

Which of the following is osteomyelitis not seen as a CS?
A. Actinobacillus suis
B. Actinobacillus equuli
C. Sleepy foal disease
D. Actinobacillus lignieresi

A

D. Actinobacillus lignieresi