Actinobacillus spp - Gutierrez Flashcards
Actinobacillus is in the ________ family
Pasteurellaceae
Culture of actinobacillus should be done on _________
MacConkey
Which is not true about Actinobacillus spp?
A. Fastidious
B. Grows on MacConkey
C. Infects a wide range of hosts
D. Some are NAD dependent
E. Has a capsule
C. Infects a wide range of hosts
FALSE: notable host restriction
What actinobacillus spp are of veterinary importance?
- A. pleuropneumoniae
- A. suis
- A. equuli
- A. lignieresii
- A. seminis
Actinobacillus seminis infects what species?
Sheep and goats
Actinobacillus equuli infects what species?
Horses and pigs
Actinobacillus lignieresii infects what species?
Bovine
Actinobacillus pleuropneumoniae infects what species?
Pigs
True or False: Actinobacillus spp forms biofilms which protect it from hostile environments
TRUE
________ plays a role in adhesion of actinobacillus spp
LPS
Secretion of ______ group of toxins are hemolytic and leukocytic
RTX
What is the predisposing factor for infection of actinobacillus?
Viral infections, trauma, stress, low maternal immunity
________ is the only actinobacillus spp that is considered a primary pathogen
Actinobacillus pleuropneumoniae
Actinobacillus pleuropneumoniae colonizes in the __________
URT of healthy pigs only
Reservoir of Actinobacillus pleuropneumoniae?
Tonsils of pigs
Which form of Actinobacillus pleuropneumoniae results in high morbidity and mortality?
Peracute / acute form
Main toxins involved in the pathogenesis of Actinobacillus pleuropneumoniae?
ApxI - most potent. hemolytic and leukocytic
- ApxII - less potent. hemolytic and leukocytic
- ApxIII - potent but not hemolytic
Actinobacillus suis colonizes in _________
URT and vagina of healthy pigs
Actinobacillus equuli subsp. equuli is known as _________
Sleepy foal disease
The chronic form of Actinobacillus equuli subsp. equuli is characterized by __________
- Purulent arthritis (joint ill)
- Suppurative multifocal nephritis
What actinobacillus equuli spp infects only horses?
Actinobacillus equuli subsp. haemolyticus
__________ actinobacillus spp causes wooden (timber) tongue
A. lignieresi
Disease development of actinobacillus lignieresi occurs after ___________
Inoculation into mucous membranes during abrasion by rough feed
Pyogranulomatous lesions formed by actinobacillus lignieresi resemble those of ___________
Actinomyces bovis
Which is not true of actinobacillus lignieresi?
A. Bone is usually unaffected
B. Facultative aerobe
C. Spreads via lymphatics
D. Abscesses can be seen on the jaw, head, neck, and limbs
B. Facultative aerobe
FALSE: Facultative anaerobe
What can be seen on growth of actinobacillus spp on sheep blood agar?
Satellitism (NAD dependence = staphylococcus required for growth) and CAMP effect (Co-hemolysin)
What vaccines are available for actinobacillus?
- Bacterins
- Apx toxins
- Apx + Transferrin binding proteins
- Apx + TBP + Type IV fimbriae
Which of the following is osteomyelitis not seen as a CS?
A. Actinobacillus suis
B. Actinobacillus equuli
C. Sleepy foal disease
D. Actinobacillus lignieresi
D. Actinobacillus lignieresi