Rheumatology Flashcards
What are Tophi?
Gout crystals + giant cells
What is Rheumatoid Factor?
An IgM against IgG F c
What is Podagra?
Big toe inflammation
What is CREST syndrome?
Calcinosis Raynaud's Esophageal dysmotility Sclerodactyly Telangiectasia
What Ab is associated with CREST?
Anti-centromere Ab
What disease have Raynaud’s syndrome?
Scleroderma
Takayasus
RA
SLE
What platelet count do most types of vasculitis have?
Low platelets
Which vasculitis has a high platelet count?
Kawasaki disease
Which vasculitis has a normal platelet count?
Henoch-Schonlein purpura
What is Osteoarthritis?
Pain worse w/activity, PIP/DIP joints
What is Rheumatoid Arthritis?
Pain worse in morning, MCP/PIP joints
What is Still’s disease?
Juvenile RA
What is Pseudogout?
Pyrophosphate crystals in knees/wrists
What is Gout?
Urate crystals in big toe, (-) birefringence
What is Myositis?
1 muscle hurts
What is Polymyositis?
> 1 muscle weak
What is Dermatomyositis?
Myosis +rash
What is Fibromyalgia?
Hurt all the time, 11 trigger points
What is Polymyalgia Rheumatica?
Weak shoulders, temporal arteritis
What is SLE=Lupus?
Meet 4 criteria: “DOPAMIN RASH”
Discoid rash
Oral ulcers
Photosensitivity
Arthritis
Malar rash
Immunologic disorder: Anti-ds DNA, Sm, Cardiolipin Ab
Neurologic disorder: seizure or psychosis
Renal failure: die of this
ANA
Serositis: pleuritis/pericarditis (Libman-Sacks endocarditis)
Hemolytic anemia
What is Scleroderma?
Tight skin, fibrosis
What is Takayasu’s Arteritis?
Pulseless Asian women, aorta inflammation
What is Polyarteritis Nodosa?
p-ANCA Ab, attacks gut/kidney, Hep B
What is Wegener’s Granulomatpsis?
c-ANCA Ab, attacks ENT, lungs, kidney
What is Goodpasture’s?
Anti-GBM Ab, attacks lung/kidney, RPGN
What is Reiter’s syndrome?
Males that can’t see, pee or climb a tree
What is Sjogren’s syndrome?
Females that have dry eyes/mouth, RA
What is Behcet’s syndrome?
Oral and genital ulcers, uveitis
What is Churg-strauss?
Asthma, eosinophils, multi organ involved
What is Felty’s syndrome?
RA, leukopenia, splenomegaly
What is Kawasaki’s disease?
“CRASH”
Conjuctivitis Rash (palm/sole) Aneurysm (coronary artery) -> MI in kids Strawberry tongue Hot (fever > 102 F for at least 3 days +cervical lymphadenopathy)
