Muscle Flashcards
Where is CK-MM found?
Muscle
Where is CK-MB found?
Heart
Where is CK-BB found?
Brain
Why should you wait 30 min after a meal before swimming?
All blood in gut and skeletal mm. have run out of ATP
How does a neurogenic muscle disease present?
Distal weakness + fasciculations
How does a myopathic muscle disease present?
Proximal weakness + pain
What is a light chain composed of?
Actin
What is a heavy chain composed of?
Myosin
What band of the sarcomere does not change length?
A band
Where are the t-tubules located?
Cardiac muscle: Z line
Skeletal muscle: A-I junction
What is Duchenne’s MD?
Dystrophin frameshift, Gower sign, calf pseudohypertrophy
What is Beckers MD?
Dystrophin missense, sx >5 y/o
What is Myotonic Dystrophy?
Birds beak face, can’t let go when shake hands
What is Myasthenic syndrome = Lambert-Eaton?
Gets stronger as day goes by, stronger w/ EMG, not small cell CA
What is a Myasthenia gravis?
Gets weaker as day goes, stronger w/ Edrophonium, weaker w/ EMG, rule out thymoma