Muscle Flashcards

0
Q

Where is CK-MM found?

A

Muscle

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1
Q

Where is CK-MB found?

A

Heart

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2
Q

Where is CK-BB found?

A

Brain

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3
Q

Why should you wait 30 min after a meal before swimming?

A

All blood in gut and skeletal mm. have run out of ATP

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4
Q

How does a neurogenic muscle disease present?

A

Distal weakness + fasciculations

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5
Q

How does a myopathic muscle disease present?

A

Proximal weakness + pain

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6
Q

What is a light chain composed of?

A

Actin

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7
Q

What is a heavy chain composed of?

A

Myosin

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8
Q

What band of the sarcomere does not change length?

A

A band

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9
Q

Where are the t-tubules located?

A

Cardiac muscle: Z line

Skeletal muscle: A-I junction

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10
Q

What is Duchenne’s MD?

A

Dystrophin frameshift, Gower sign, calf pseudohypertrophy

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11
Q

What is Beckers MD?

A

Dystrophin missense, sx >5 y/o

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12
Q

What is Myotonic Dystrophy?

A

Birds beak face, can’t let go when shake hands

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13
Q

What is Myasthenic syndrome = Lambert-Eaton?

A

Gets stronger as day goes by, stronger w/ EMG, not small cell CA

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14
Q

What is a Myasthenia gravis?

A

Gets weaker as day goes, stronger w/ Edrophonium, weaker w/ EMG, rule out thymoma

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15
Q

What is Multiple Sclerosis?

A

Anti-Myelin Ab, young woman w/ vision problems, sx come and go

16
Q

What is a Metachromatica Leukodystrophy?

A

Arylsulfatase deficiency, kid with MS presentation

17
Q

What is Ataxia Telangectasia?

A

Spider veins, Ig A deficiency

18
Q

What is Friedreich’s ataxia?

A

Retinitis pigmentosa, scoliosis

19
Q

What is Adrenal Leukodystrophy?

A

Carnitine shuttle problem, adrenal failure

20
Q

What is Guillain-Barre?

A

Ascending paralysis, 2 wks after URI

21
Q

What is ALS?

A

Middle age male w/ Fasciculations, descending paralysis, no sensory problems

22
Q

What is Werdnig-Hoffman?

A

Fasciculations in a newborn, no anterior horns

23
Q

What is Polio?

A

Asymmetric Fasciculations in child, 2 wk after gastroenteritis

24
Q

What is Choreoathetosis?

A

Dance-like movements, wringing of hands, quivering voice

25
Q

What is Atonic cerebral palsy?

A

No muscle tone, floppy