RHEUMATOLOGY Flashcards

1
Q

Morning stiffness
Joint pain
Joint swelling
Dx and treatment

A

Juvenile Rheumatoid Arthritis
Tx: nsaid

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2
Q

Most common resentstion of arthritis in SLE

A

Symmetrical arthritis of joints I the hands

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3
Q

Atlabtoaxial joint
Ra orOA

A

RA

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4
Q

Cervical and lumbar spine
RA Or OA

A

OA

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5
Q

1st carpometacarpal joint
1st Metatarsophalangeal joint
DIP
PIP
Knee joint
Hip Joint

A

OSTEOARTHRITIS

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6
Q

Most commonly affected in Pdeudogout

A

Knee

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7
Q

Non itchy, non-pitrinf swelling, laryngeal edema, abdominal pain,Vomiting and diarrhoea
Dx and investigation?

A

Hereditary angioedema
C1 and C4 levels

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8
Q

Mouth Ulverstone
Ain’t and swelling 8n both wrists and MCP joints
Dx?

A

SLE

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9
Q

Treatment of choice for acute gout

A

NSAIDS

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10
Q

Treatment for chronic gout

A

Allopurinol

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11
Q

Pain and stiffness hips and shoulders
Elevated ESR
Age over 50 years, typically 60-70

A

Polymyalgia Rheumatica

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12
Q

Specific antibody test for diagnosing SLE

A

Anti- d’s DNA

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13
Q

Screening test for SLE

A

Antinuclear Antibody

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14
Q

Specific antibody for idiopathic inflammatory myopathies

A

Anti jo 1 antibody

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15
Q

Sensitive marker for mixed connective tissue disease

A

Anti,-ribonucleoprotein antibody

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16
Q

Nodules
No skin erosions
Arthralgias in multiple joints

Dx:
Tx

A

Rheumatoid Nodulosis
Intralesional steroid injection

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17
Q

Both joints red, warm and tender
Ankle pain
Chronic alcohol use and binge drinking
Needle aspiration: needle shaped monosodium aspirate
Dx
Tx

A

Acute Gout
Prednisolone 50 mg / day

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18
Q

Left sided throbbing headache
Jaw claudication with unexplained fever
Inv
Dx

A

Temporal artery biopsy
Giant cell arthritis

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19
Q

Woman rheumatoid
On methotrexate and Hydroxychloroquine
Advice during pregnancy?

A

Yes continue to hydroxycholoroquine
But stop with methotrexate

20
Q

Treatment for Giant cell ateritis

A

Rednisolone 40-60 mg mg/d

21
Q

Atrophy of vast deferens

A

Sweat Chloride test
Cystic fibrosis

22
Q

Calcinosis
Raynauds phenomenon

A

Abticebtromere antibodies
Systemic Sclerosis

23
Q

Recurrent swelling of her face, arms and legs
Nonliving and nonpruiritic swelling
Inv
Dx

A

C1 AND c4 levels
Hereditary angioedema

24
Q

Multiple sclerosis
Approx one person in how many

A

1000

25
Q

Hypertension
Indapamide
Binge drinking every night

A

Acute Gout

26
Q

ANCA positive
antiproteinase PR3
Antimyeloperoxidase or MpO

A

Wegeners Granulomatosis

27
Q

Low back pain
Morning stiffness

A

Inflammatory Arthropathy

28
Q

Dry mouth, gritty sensation in the eyes
Difficult to speak, no history of DM
Salivary glands enlarged
Management?

A

Schirmier test and measurement of antibodies

29
Q

Unable to climb stairs
Rash on face, weakness on hip and shoulder girdle
Purplish red discolorations OT the eyes and erythermatous discolorations of fingers and joints
Dx?

A

Dermatomyositis
- heliotrope rash
**discoloration of the eyes that extends to the joints and extremities

30
Q

Pain and swelling of wrists and knees
Several months fatigue
MCP joints and wrists tender and warm
Dx and
Inv

A

Rheumatoid Arthritis
And Rheumatoid Factor

31
Q

Painful swollen knee
Cloudy fluid, wbc 50,000 mm3
More than 90,% PMN leukocytes
Glucose fluid level decreased
Dx?

A

Infectious Arthritis

32
Q

Myopathy
Noncaseating Granulomas
Dx,?

A

Sarcoidosis

33
Q

Worsening headaches,
Episodes of transfer visual loss
A Nd diploma
Jaw muscle stops chewing
Tender nodular at right temporal artery
Normocystic anaemia
Sedimentation rate 95
Dx?

A

Temporal arthritis

34
Q

What is the most feared complication of temporal arthritis?

A

Blindness

35
Q

Exposed to a children with febrile illness and rash

A

Parvovirus

36
Q

Highest specificity for rheumatoid arthritis?

A

Anti Citrullinated Peptide Antibody

37
Q

Ongoing back pain
Ain’t is severe at night and gets better after getting up and jojbt stiffness in the morning
Inv?
Dx¿?

A

Plain xrqy of the sacroiliac joints
Analysing spondylositis

38
Q

What causes the increase risk for pseudogout

A

Hypothyroidism

39
Q

What are the other factors for Pseudogout?

A

Haemochromatosis
Hyperparathyroidism
Hypercalcaemia
Hypomagnesemua
More than 70 years.family history

40
Q

Joint pain both hands
Stiffness lasting for hours once she wakes up in the morning
Nocturnal pain
Swelling around MCP and PIP
Drug of choice?

A

Rheumatoid Arthritis
Doc: Methotrexate

41
Q

Frequent fatigue and joint pain
Weight loss
Malar rash
And oral ulcers
SLE
What is incorrect about SLE?

A

Anti Smith antibody is highly sensitive for SLE

42
Q

Knee pain
Negative birefringent test

A

Gout

***needle shaped monosodium urate crystals with brightly birefringent in polarised light with negative elongation

43
Q

Drugs that doesn’t cause SLE

A

Nitrofurantoin

44
Q

Interphalangeal joints tender and rash noted on cheeks and nose
What initial investigation to do on this?

A

Antinuclear antibodies
- SLE - best initial screening test

45
Q

What are the clinical symptoms of SLE

A

Arthritis
Malar rash
And anaemia

46
Q

Generalised pain to the neck and shoulder girdle, elbow, low back pain and legs

A

Fibromyalgia
- pain in all 4 quadrants in the body

47
Q

Pain and swelling around the wrists hand joints more than 1 hr
Which is correct regarding the dx of rheumatoid Arthritis?

A

Anti CCp sensitivity is 50-60 percent
Specificity is 95-98%