High Yield 2 Flashcards
diarrhea, vomiting , weight loss and HYPERCALCEMIA
ZES
What is the initial test for a patient with suspected celiac disease?
TgT-IgA test - most sensitive test , the alternative is the anti-endomysial antibody test
Biopsy - the gold standard
Malabsorption, arthritis + lymphadenopathy
+ PAS-positive granules in lamina propria
Whipple Disease
Treat with long term antibiotics
Best initial test for Carcinoid Syndrome
Urine levels of 5- HIAA
while the CT scan and IN-111 octreotide scan is used to localize the tumor
flushing, diarrhea, abdominal cramps, right sided cardiac valvular lesions
Carcinoid Syndrome
tx: Octreotide and Surgical resection
What Vitamin deficiency does patients with carcinoid syndrome develop?
Vitamin B3 deficiency = ie Niacin deficiency
pellagra - Diarrhea, Dermatitis, Dementia
Most common cause of SBO in adults
Adhesions
Which condition is associated with the development of ileus
Diabetes Mellitus
hypokalemia
Most accurate test for mesenteric ischemia
CT angiography - gold standard
CT scan - best initial test
significant distention, tympany and tenderness, fever and signs of shock suggest perforation/peritonitis or ischemia / necrosis
Large Bowel Obstruction
(Colon Cancer)
Most common cause of Lower GI bleed in patients > 40
Diverticulosis - most common in sigmoid colon
risk factors: low fiber and high fat diet, older age and connective tissue disorder
- outpouching of the mucosa and submucosa that herniate the colonic muscle layers
Inv:
Colonoscopy - is for diverticulosis
while CT scan is for Diverticulitis
Pt with aortic valve endocarditis - given with Iv antibiotics - culture positive for S bovis . next step?
Colonoscopy
weight loss, anorexia, blood in stool, obstruction in left sided lesions, bright red in rectal lesions
Colorectal Cancer
Most commonly affected site in the Ischemic Colitis
Left Colon
Most commonly at the splenic flexure by the watershed area
Symptoms of Ischemic Colitis
lower abdominal pain, diarrhea after meals, exertion, fever may suggest bowel necrosis
upper GI bleed is classified as one above the
Jejunum
Transmural inflammation is seen in:
skip lesions
Crohn Disease
Treatment for gallstone ileus
Laparotomy with stone extraction
Elevated ALP and bilirubin is seen in
Cholestasis
Most common causes of Chronic Viral Hepatitis are
HBV, HCV
( busy - chronic viral hepatitis)
p-ANCA and onion skinning sclerosis
Primary Sclerosing Cholangitis
Which medication slows the disease of progression of Primary Biliary cholangitis
Ursodeoxycholic acid
(cholestyramine for pruritus)
Obese, diabetic patient who develops hepatomegaly with increased LFTS and hepatitis/ alcoholism
Insulin Resistance
Most common type of Primary Liver Cancer
Hepatocellular carcinoma
Autosomal recessive disorder that results in defective copper transport and subsequent accumulation and deposition of copper in the liver and the brain (psychosis, delusions)
Wilson Disease
tx: Penicillamine