Revision Powerpoint GI Flashcards
bloody diarrhoea, fragmented RBC’s, undercooked hamburgers, metallic green stool cultures?
E. coli 0157
red macules on body on examination?
salmonella Typhi
playing with turtles
undercooked chicken
stale chicken?
H. salmonella enterididis
bloody diarrhoea, haemorrhagic mucosa with ulcerations on distal colon?
shigella dystenteria
india
severe dehydration
watery (“rice water”) diarrhoea?
vibrio cholerae
unpasteurised/raw milk
guillian barre syndrome?
campylobacter jejuni
what are the symptoms of norovirus?
sudden explosive diarrhoea and vomiting
no blood
what is proctitis?
disease affecting only yht rectum
what is pancolitis?
disease involving whole olon
UC can sometimes spread proximal to the ileocaecal valve, true or false?
false
crypt abscesses in UC or crohns?
UC
treatment for crohns?
immunosuppression
steroids
anti-TNF
surgery not curative and can result in short gut but is sometimes used
treatment for UC?
5-ASA (mesalazine) Corticosteroids anti TNF immunosuppresants surgery
prehepatic jaundice?
unconjugated bilirubin increased
conjugatd bilirubin = normal
AST/ALT = normal
ALP/GGT = normal
Intrahepatic jaundice?
unconjugated bilirubin = increased
conjugated bilirubin = increased
AST/ALT = increased
ALP/GGT = normal
posthepatic jaundice?
unconjugated bilirubin = normal
conjugated bilirubin = increased
AST/ALT = normal
ALP/GGT = increased
how do conjugated and unconjugated bilirubin cause different symptoms?
unconjugated = normal urine and stool conjugated = pale stools and dark urine
normal urine and stools?
prehepatic
dark urine, normal stools?
hepatic
dark urine, pale stools?
post hepatic
3 causes of unconjugated hyperbilirubinaemia?
haemolysis
impaired hepatic uptake (drugs, CCF)
impaired conjugation (gilbert’s syndrome)`
2 causes of conjugated hyperbilirubinaemia?
hepatocellular injury
cholestasis
what is cholelithiasis?
gallstones
diagnosis of gallstones?
ultrasound
dilation of the bile ducts
cholecystitis and biliary colic present very similarly, what is the main difference between them?
cholecystitis has an inflammatory component (raised WCC)
beaded appearance on ERCP?
PSC
PSC treatment?
liver transplant is only cure
chronic granulomatous inflammation of interlobular bile ducts?
PBC
HBsAg?
always present in infection, either acute or chronic
HBeAg?
hows hep virus is actively multiplying
Anti-HBs?
immunity to hep B
either previously infected or vaccinated
Anti-HBe?
immune system has responded against Hep B and virus is not replicating
Anti-HBc?
infected with Hep B but does not provide any protection against infection
HBV DNA?
amount of Hep B virus in bloodstream
indicates how actively virus is multiplying
vesicular rash + weight loss?
coeliac disease
pyoderma gangrenosum
erythema nodosum?
IBD
14C breath test?
bacterial overgrowth
Mallory’s hyaline bodies?
alcoholic liver disease (acute hepatitis) and chronic active hepatitis
onion skinning fibrosis
beading of bile ducts?
PSC
Signet ring seen on biopsy?
Linitisplastica
diffuse stomach cancer
thumb printing on X ray commonly at splenic flexure?
ischaemic colitis
charcots triad?
fever
jaundice
abdo pain
secondary to acute cholangitis
causes of abdominal mass
A CHEMICAL
AAA crohns hernia enlarged organ malignancy intussusception Cyst or abscess appendicitis lymphadenopathy
Causes of bowel obstruction?
BATH VIPS
bolus adhesions tumour hernia volvulus intussusception pseudo-obstruction stricture
where is the virchows node and what does it suggest if enlarged?
supra-clavicular fossa
suggests gastric cancer
colicky loin pain radiating to groin?
uretic colic
what type of mouth disease do people with crohns get?
stomatitis gangrenosum
iliac fossa pain, positive pregnancy test?
ectopic pregnancy
asterixis (liver flap)?
encephalopathy
leuconychia?
hypoalbuminaemia
koilonychias?
iron deficiency anaemia (IDA)
angular stomatitis?
IDA
buccal pigmentation?
peutz-jeghers syndrome
what is peutz-jaghers syndrome?
autosomal dominant
benign polyps in GI tract and hyperpigmentation on lips and oral mucosa
glossitis?
B12 deficiency
apthous ulceration?
crohns
craggy hepatomegaly?
liver malignancy
bronzed diabetic?
haemochromatosis