Resp Empirical Treatments

Question 1

Infective exacerbation of COPD?

Answer 1

amoxicillin then doxycycline

only if purulent sputum

Question 2

H. Pylori infection?

Answer 2

1 week of:

• omeprazole
• clarithromycin
• Amoxicillin/metronidazole

Question 3

campylobacter infection?

Answer 3

ciprofloxacin or erythromycin (if co-morbidity)

Question 4

Shigella infection?

Answer 4

ciprofloxacin or azithromycin

Question 5

salmonella infection?

Answer 5

ciprofloxacin or cefotaxime (if co-morbidity)

Question 6

Typhoid?

Answer 6

ciprofloxacin or cefotaxime

Question 7

C. Diff infection?

Answer 7

Non-severe = oral metronidazole
Severe = Oral vancomycin
(diagnosed by CDT in stool)

Question 8

Biliary tract infection?

Answer 8

Ciprofloxacin or gentamicin or cephlasporin

Question 9

Peritonitis?

Answer 9

metronidazole + gentamicin

Question 10

Endocarditis blind therapy?

Answer 10

flucoxacillin + gentamicin

Question 11

Mild/moderate CAP?

Answer 11

amoxicillin

Question 12

Severe CAP?

Answer 12

CO-amoxiclav + clarythromicin

Question 13

HAP?

Answer 13

early onset = co-amoxiclav

late onset = broad spectrum cephlasporin

Question 14

side effects of rifampicin?

Answer 14

orange secretions
rash
hepatotoxicity/hepatitis

Question 15

Izoniazid?

Answer 15

tingling
parasthesiae of extremities
hepatitis

Question 16

Pyrazinamide?

Answer 16

joint pain
rash allergic reaction
yellow skin/eyes
gout
hepatitis

Question 17

ethambutamol?

Answer 17

colour blindness to blindness

hepatitis?

Question 18

TB treatment?

Answer 18

2 months RIPE, 4 months RI

Question 19

how is osteoporosis diagnosed?

Answer 19

DEXA bone scan

Question 20

antibiotics for unknown source of infection?

Answer 20

IV amoxicillin + metronidazole + gentamicin
(consider adding flucox if concerned about staph)
if penicillin allergic - IV vancomycin + metronidazole + gentamicin

Question 21

is bronchopneumonia neutrophilic or eosinophilic?

Answer 21

neutrophilic

Question 22

0-2 CURB65 score?

Answer 22

mild pneumonia

amoxicillin/doxycycline

Question 23

3-5 CURB65 score?

Answer 23

severe pneumonia
IV co-amoxiclav and IV clarithromycin
then step down to oral doxycycline

Question 24

HAP or aspiration pneumonia?

Answer 24

IV amoxicillin + metronidazole + gentamicin

step down to co-trimoxazole + metronidazole orally

Question 25

COPD exacerbation?

Answer 25

SABA/SAMA > check FEV1

• > 50% = LABA/LAMA, then LABA + ICS, then add LAMA
• <50% = LAMA/LABA + ICS, the LABA + ICS + LAMA