Review

Question 1

Ix EBV

Answer 1

serology for anti-EBV antibodies

Question 2

if EBV is negative and someone has proliferative lymphocytes what should be considered?

Answer 2

HIV test

Question 3

blood film of glandular fever?

Answer 3

atypical lymphocytes

Question 4

EBV infiltrates what cells

Answer 4

B and T lymphocytes

Question 5

amoxicillin rash in a tonsillitis patient…

Answer 5

consider EBV

Question 6

mets tend to spread regionally/generally

Answer 6

regionally

Question 7

what are smear cells

Answer 7

lymphocytes whose cell membranes have ruptured in preparation of the blood film

Question 8

smear cells on blood film…

Answer 8

CLL

Question 9

hodgkins is more common in who?

Answer 9

young esp women

Question 10

disease ___ the diaphragm is more common

Answer 10

above

Question 11

what symptoms are more common of hodgkins disease than NHL?

Answer 11

B symptoms
itch
alcohol induced pain

Question 12

causes of neutrophilia

Answer 12

bacterial infection
inflammation
trauma/post op
corticosteroids
MPD

Question 13

causes of lymphocytosis

Answer 13

viral infection
childhood response to infection
leukaemia

Question 14

how to differentiation HL from NHL

Answer 14

LN biopsy

Question 15

how is lymphoma staged?

Answer 15

CT

PET

Question 16

cytotoxic drug side effects?

Answer 16

bone marrow suppression
gut mucosal damage
hair loss

Question 17

Ix pancytopenia

Answer 17

retic count
B12 folate
abdo USS
bone marrow biopsy

Question 18

causes of hypocellular marrow

Answer 18

drug induced aplasia

aplastic anaemia

Question 19

cause of hypercellular marrow

Answer 19

infiltration eg by cancer
peripheral destruction
hypersplenism

Question 20

splenectomy can treat what autoimmune conditions

Answer 20

ITP

AIHA

Question 21

what is the spleen needed for

Answer 21

immunity against encapsulated organisms (meningococcus, pneumococcus, HiB)
remove red blood cells