Interpreting Blood Counts Flashcards
what are reactive changes?
bone marrow is reacting to something
what is rouleaux
clumping together of red cells
megaloblastic blood count, female, autoimmune Hx…
pernicious anaemia
how would you diagnose pernicious disease?
intrinsic factor autoantibodies
what can you cause if you give someone folate if theyre B12 deficient
demyelination
a bone marrow of megaloblastic anaemia would be hypo/normo/hypercellular
hypercellular
why are you jaundiced in B12 deficiency?
premature red cell destruction in the BM causing excess bilirubin production
signs of toxic changes to neutrophils?
granules
vacuoles
causes of neutrophilia
steroids
infection eg sepsis
FBC results of DKA
reactant neutrophilia
crenated red cells
what test would help confirm suspicions of a haemolysis?
retic count
you should do genetic testing to confirm hereditary spherocytosis T or F
F, if you have a strong history and blood film you dont need to
Tx hereditary spherocytosis
folic acid
splenectomy if bad
why do people with hereditary spherocytosis have small stature
chronic marrow hyperplasia
why can MCV appear normal when some red cells are fragmented and some are big?
there are large and small cells which can cancel each other out
