Restrictive3 Flashcards
1
Q
Mutations. Rare cause of neonatal RDS. Fatal w/o lung transplant.
A
Congenital pulmonary alveolar proteinosis
2
Q
Very uncommon. Secondary to silicosis, malignancies, and immunodeficiencies
A
Secondary PAP
3
Q
Lungs heavy and large. Minimal inflammatory infiltrate. Dense intra-alveolar granular precipitate PAS+
A
PAP
4
Q
Can resolve or progress to severe respiratory failure
A
PAP
5
Q
Treated by bronchoalveolar lavage to remove precipitate
A
PAP
6
Q
Most cases. Anti GM-CSF (Granulocyte macrophage colony stimulating factor) antibodies that impair surfactant clearance by alveolar macrophages
A
Acquired pulmonary alveolar proteinosis
