Restrictive2

Question 1

Has noncaseating granulomas with schaumann bodies and asteroid bodies

Answer 1

Sarcoidosis

Question 2

Laminated concretions of Ca and proteins

Answer 2

Sarcoidosis

Question 3

Stellate inclusions in giant cells

Answer 3

Sarcoidosis

Question 4

Hilar and mediastinal LNs calcified. Spleen enlarged. Granulomas in portal tract of liver. Bone marrow of phalangeal bones in hands and feet involved

Answer 4

Sarcoidosis

Question 5

Bronchoscope can biopsies high yield

Answer 5

Sarcoidosis

Question 6

Iritis and lacrimal gland inflammation (dacroadenitis)

Answer 6

Sarcoidosis

Question 7

Dacroadenitis and BL involvement of parotid, submaxillary, and sublingual glands

Answer 7

Mikulicz syndrome. Sarcoidosis

Question 8

Anorexia, weight loss, night sweats

Answer 8

Sarcoidosis

Question 9

Unpredictable course. 2/3rds recover w/o any problems. 20% get permanent loss of visual/lung fn. 10-15% die of cardiac, lung, or CNS disease (usually progressive pulmonary fibrosis)

Answer 9

Sarcoidosis

Question 10

Hilar lympadenopathy sarcoidosis

Answer 10

Best prognosis

Question 11

Immunologically mediated. Prolonged exposure to inhaled organic dusts and occupational antigens

Answer 11

Hypersensitivity pneumonitis

Question 12

Has type 3 immune complex rx and type 4 hypersensitivity granulomatous rx

Answer 12

Hypersensitivity pneumonitis

Question 13

Inhaled spores of actinomycetes

Answer 13

Farmers lung - hypersensitivity pneumonitis

Question 14

Noncaseating granulomas

Answer 14

Hypersensitivity pneumonitis

Question 15

Occurs in previously sensitized pts. Fever, SOB, cough, increased WBC 4-6 hrs after re-exposure

Answer 15

Acute attacks of hypersensitivity pneumonitis

Question 16

Progressive SOB and cyanosis. Decreased compliance and TLC.

Answer 16

Chronic hypersensitivity pneumonitis

Question 17

Hypersensitivity to inhaled antigens (not food or drugs). Rapid fever, SOB, and hypoxemia > respiratory failure. Bronchoalveolar lavage shows >25% eosinophils. Treat with steroids

Answer 17

Acute eosinophilic pneumonia

Question 18

Hypersensitivity to food or drugs (sulfa). Transient lung lesions and blood eosinophilia. Alveolar septa with eosinophils and giant cells. Benign, self limited

Answer 18

Simple pulmonary eosinophilia (loefflers)

Question 19

Parasitic, bacterial, and fungal infections. Associated with asthma and aspergillosis. Can cause chronic lung injury and fibrosis

Answer 19

Secondary pulmonary eosinophilia

Question 20

Associated with autoimmune disease. Eosinophil and lymphocyte aggregates in septal walls and alveolar spaces. Increased fever, night sweats, and SOB. Treat with steroids

Answer 20

Chronic eosinophilic pneumonia

Question 21

All patients smokers. Alveoli filled with pigment laden smokers macrophages

Answer 21

Desquamative interstitial pneumonitis

Question 22

4-5th decade. Males. Insidious onset. Clubbing. Excellent response to steroid treatment (100%)

Answer 22

Desquamative interstitial pneumonitis

Question 23

Significant symptoms SOB and cough. Smokers macrophages in peribronchiolar regions, respiratory bronchioles, and alveolar ducts

Answer 23

Respiratory bronchiolitis associated interstitial lung disease

Question 24

Mild fibrosis of peribronchiolar region w/ centrilobar emphysema. Improves with smoking cessation

Answer 24

Respiratory bronchiolitis associated interstitial lung disease

Question 25

Increases in CD4 Thelper cells, IL2/IL8, TNF, IFN -gamma, macrophage inflammatory protein

Answer 25

Sarcoidosis