Fenger Flashcards

1
Q

Parainfluenza and RSV

A

Paramyxovirus

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2
Q

HN and F

A

Parainfluenza and RSV - paramyxovirus

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3
Q

RSV and metapneumonia

A

Pnemovirus

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4
Q

F

A

RSV and metapneumonia - pneumovirus

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5
Q

For paramyxovirus ________ protein must be proteolytically cleaved to be active

A

F

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6
Q

4 types. Type 1 = Croup, ARD, colds, runny nose. Type 2 - croup. Types 3+4 = ARD, bronchitis, and pneumonia

A

Parainfluenza virus

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7
Q

Lower respiratory tract disease in infants and young children. Bronchiolitis and pneumonia.

A

Pneumovirus - RSV and metapneumonia

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8
Q

Maternal IgG not protective. May enhance severity

A

RSV and metapneumonia - pneumoviruses

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9
Q

Coxsackie A and B, echovirus, rhinovirus

A

Picornaviridae

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10
Q

Respiratory disease (pharyngitis) along with hand, foot, and mouth disease

A

Coxsackie A type 16

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11
Q

+ polarity, icosahedral capsid, no envelope.

A

Picornaviridae

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12
Q

Respiratory illness more severe in children and teenagers. Especially with asthma

A

Enterovirus D68

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13
Q

Nasopharyngeal isolation only. Over 100 serotypes. 2-4 day incubation period

A

Rhinoviruses

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14
Q

New serotypes that can cause lower respiratory tract infections with symptoms that could be confused with H1N1

A

Rhinoviruses

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15
Q

+ very large RNA. Helical nucleocapsid. Two glycoproteins in envelope that form pep lovers. Replicates in cytoplasm. Buds to get envelope

A

Coronaviridae

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16
Q

5 antigenic groups. Group 2 includes coronavirus OC43, SARS. Isolated from 2 pneumonia pts

A

Coronaviruses

17
Q

Virus particle binds to cell surface receptor (metalloprotease and coreceptor neuraminic acid). Forms replicative intermediate (+/- RNA)

A

Coronaviridae

18
Q

Binds to receptor angiotensin converting enzyme 2 (ACE2) on epithelial cells.

A

SARS

19
Q

Derived from bats and civet cats

A

SARS

20
Q

+DS DNA, icosahedral protein capsid. Replication and viral assembly in nucleus

A

Adenovirus

21
Q

Capsid has 252 Capsomers (240 hexons and 12 pentons). Pentons consist of base and fibers (fibers have antigenic characteristics)

A

Adenovirus

22
Q

Types ____________ of adenovirus most important

A

4 and 7

23
Q
  • RNA. Cytoplasmic replication. Helical nucleocapsid. RNA dependent RNA Pol. Envelope with glycoprotein spikes
A

Paramyxoviridae