Fenger

Question 1

Parainfluenza and RSV

Answer 1

Paramyxovirus

Question 2

HN and F

Answer 2

Parainfluenza and RSV - paramyxovirus

Question 3

RSV and metapneumonia

Answer 3

Pnemovirus

Question 4

F

Answer 4

RSV and metapneumonia - pneumovirus

Question 5

For paramyxovirus ________ protein must be proteolytically cleaved to be active

Answer 5

F

Question 6

4 types. Type 1 = Croup, ARD, colds, runny nose. Type 2 - croup. Types 3+4 = ARD, bronchitis, and pneumonia

Answer 6

Parainfluenza virus

Question 7

Lower respiratory tract disease in infants and young children. Bronchiolitis and pneumonia.

Answer 7

Pneumovirus - RSV and metapneumonia

Question 8

Maternal IgG not protective. May enhance severity

Answer 8

RSV and metapneumonia - pneumoviruses

Question 9

Coxsackie A and B, echovirus, rhinovirus

Answer 9

Picornaviridae

Question 10

Respiratory disease (pharyngitis) along with hand, foot, and mouth disease

Answer 10

Coxsackie A type 16

Question 11

+ polarity, icosahedral capsid, no envelope.

Answer 11

Picornaviridae

Question 12

Respiratory illness more severe in children and teenagers. Especially with asthma

Answer 12

Enterovirus D68

Question 13

Nasopharyngeal isolation only. Over 100 serotypes. 2-4 day incubation period

Answer 13

Rhinoviruses

Question 14

New serotypes that can cause lower respiratory tract infections with symptoms that could be confused with H1N1

Answer 14

Rhinoviruses

Question 15

+ very large RNA. Helical nucleocapsid. Two glycoproteins in envelope that form pep lovers. Replicates in cytoplasm. Buds to get envelope

Answer 15

Coronaviridae

Question 16

5 antigenic groups. Group 2 includes coronavirus OC43, SARS. Isolated from 2 pneumonia pts

Answer 16

Coronaviruses

Question 17

Virus particle binds to cell surface receptor (metalloprotease and coreceptor neuraminic acid). Forms replicative intermediate (+/- RNA)

Answer 17

Coronaviridae

Question 18

Binds to receptor angiotensin converting enzyme 2 (ACE2) on epithelial cells.

Answer 18

SARS

Question 19

Derived from bats and civet cats

Answer 19

SARS

Question 20

+DS DNA, icosahedral protein capsid. Replication and viral assembly in nucleus

Answer 20

Adenovirus

Question 21

Capsid has 252 Capsomers (240 hexons and 12 pentons). Pentons consist of base and fibers (fibers have antigenic characteristics)

Answer 21

Adenovirus

Question 22

Types ____________ of adenovirus most important

Answer 22

4 and 7

Question 23

• RNA. Cytoplasmic replication. Helical nucleocapsid. RNA dependent RNA Pol. Envelope with glycoprotein spikes

Answer 23

Paramyxoviridae