Rest of DNA viruses Flashcards
Where does Pox virus replicate? why is this strange
in the cytoplasm
because DNA virus
how did the smallpox (poxvirus) vaccine work
induce immunity through introduction of avirulent form of poxvirus
how does smallpox spread
droplet transmission >5 microns 3-6 feet
aerosol transmission <5 micron suspended in air for long periods of time
where do small pox lesions accumulate
dense on face and palms with centrifugal spread and ulcerate deep
what is molluscum contagiosum and what causes it
small 1-2 mm white bumps with central dimple caused by poxvirus
What are the 3 members of PaPoVa viruses
PApilloma virus
Polyomavirus (BK and JC)
VA: simian vacuolating virus
what strains of HPV are assoc with cervical dysplasia
type 16 and 18
The HPV vaccine is protective against what strains
16 18 6 and 11
What is presentation of the BK polyomavirus
mild or asymptomatic infection in children
usually in immunocompromised causes nephritis and ureteral stenosis in renal transplant patients and hemorrhagic cystitis in bone marrow transplant rejection
What does JC polyomavirus cause in immunocompromised patients
Progressive Multifocal Leukoencephalopathy
PML
CNS white matter damage
memory loss, poor speech and incoordination
What do the adenoviruses cause
URI
coughing and sneezing in children especially
rhinitis, conjunctivitis, sore throat and cough
what are the most common respiratory illnesses in children
RSV, metapneumovirus, parainfluenza, rhinovirus and adenovirus
What are the second most common viral causes of endemic diarrheal illness in infants and children
enteric adenoviruses
What does parvovirus cause in childhood
erythema infectiosum
fever and slapped face rash on cheeks
which DNA virus is circular
the PAPOVAviruses
