Helminths Flashcards
What are nemotodes and what are playhelminthes
nemotodes are round worms
playhelminthes are flat worms
What intestinal nematodes are acquired by ingestion of eggs
Ascaris lumbricoides, Trichuris richuria and Enterobius vermicularis(pin worm
What round worms usually penetrate skin of feet
Necator amricanus and Stronglyoides stercoralis
What round worm is ingested in port meat with larvae
Trichincella spiralis
What round worms invade the lung at some point in their cycle
Ascaris lumbricoides, Necator Americanus and Stronglyoides stercoralis
Where and how do people acquire ascaris lumbricoides
mountainouse and tropical areas souther US
consume food with the eggs
Where do the larvae of Ascaris grow
in lung alveolie then coughed up swallowed and mature in intestines
What happens with the eggs of Strongyloides stercoralis
Autoinfection-larvae penetrate intestine directly
Direct cycle- larvae pass out in feces and infect next person
Indirect- in soil the filariform larvae develop into male and female adults then fertllze eggs and the larvae hatch and reinfect
What is involved in severe infections with Ascaris
worm invasion into bile ducts, gall bladder and appendix and liver
in lung have pulmonary infiltrate on CXR with high eosinphilia
Dx of any types of the worms?
eggs in feces
What drugs are used to treat intestinal nematodes
Mebendazole
Albendazole
Thiabendazole
To selectively target Enterobius or Necator or Ascaris what drug can you give
pyrantel pamoate
What can an infection by hookworms cause
Ascaris
Necator
iron deficiency anemia since suck blood
What do you avoid during Tx of Stronglyoides stercoralis
prednisone or other steroids because can result in severe auto infection of pneumonia ARDS and multi-organ failure
What is the enterotest
long nylon string is swalled and later pulled out of the mouth to see larvae of stronglyoides
What is the sensitive test for stronglyoides infection
ELISA Ab assay
Describe the cycle of Trichinella Spiralis
adult males are passed in feces
females penetrate intestinal mucosa and lay thougsands of larvae that enter blood and spread to organs and skel muscle
What are the symptoms of Trichinella Spiralis infection
1 week after intestinal invasian there may be fevers and musclar aches
How do you Dx trichinella piralis
serologic tests or muscle biopsy
Increase levels of eos
increased serum muscle enzymes like CPK
What is the whipworm
Trichuris trichuria
how come pinworm and whipworm do not have elvated eosinphilis
because there is no transit outside of the intestine
Where do the whip worm larvae adhere
cecum and ascending colon
Why is there no autoinfectino with whipworm
eggs need to incubate 3-6 weeks in soild before infective
PAtient has feces that have little football with bumps on the end
trichuris trichuria infection
whipworm
What are symptoms of whipworm infection
diarrhea and abdominal pain
What is the pinworm and where does it mature
Enterobius vermicularis
matures in the ascending colon
What is unique about the female enterobius worm
at night migrates to perianal area where she lays her egs causing severe perianal itching