Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

LAST EXAMMMMMM Year I > Herpes Viruses > Flashcards

Herpes Viruses Flashcards

1
Q

What holds the herpes viruses latent

A

cell mediated immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What effect of herpes viruses have on the immune system

A

cytopathic

become multinucleate syncytial cells with intranuclear inclusion bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

where do the herpes viruses hang out being latent

A

in the sensory ganglia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what supset of herpes viruses cause cell destruction

A

the alpha group
herpes simplex 1 and 2
herpes zoster

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the other herpes viruses and their corresponding subtypes

A

CMV is beta

EBV is gamma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how does transmission of herpes simplex 1 and 2 occur

A

direct inoculation of much-cutaneous surfaces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are some of the clinical manifestations of herpes siplex

A 
gingivostomatitis
genital herpes
herpetic keratitis
neonatal herpes
herpetic whitlow
disseminated herpes
encephalitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the signs of gingivostomatitis

A

painful swollen gums and mucous membranes with vesicles
fever and systemic symptoms
resolve in 2 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are the signs of genital herpes

A

fever, HA, vaginal and urethral discharge
enlarge d lymph nodes
blisters and painful or painless ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the most common infectious cause of corneal blindness in the US

A

herpetic keratitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what can neonatal herpes cause

A

transplacental viral transfer

congenital defects or intrauterine death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is herpetic whitlow

A

HSV infection of the finger that is painful, hot, swollen and red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when does disseminated herpes happen? and where?

A

immunocompromoised patients

liver, lung and GI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the most common cause of viral encephalitis in the US

A

HSV-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the signs of HSV-1 encephalitis

A

fever and focal neurological abnormalities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the TORCHES that cross placenta

A 
Toxoplasmosis
Rubella
CMV
Herpes HIV
Syphilis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

where does varicell ainfect and what occurs

A

infects respiratory tract then after 2 week incubation causes viral dissemination in blood

18
Q

What are symptoms of varicella infection

A

fever, malaise, HA with characteristic rash that starts on face and trunk then spreads to entire body

19
Q

What does the rash look like in Varicella

A

rose petal with dew on top(fluid vesicle)
becomes cloudy and ruptures then scab over
arise in crops or patches

20
Q

Patient has hard red lesions that have central depression and seem to be all over the body in the same state
likely Dx?

A

small pox

21
Q

How does shingles or zoster occur

A

stressed state or lowered cell mediated immunity the latent varicella zoster virus replicates and migrates to cutaneous nn

22
Q

does singles occur in adults that have not had chickenpox

A

no the adults contract chicken pox

23
Q

what adult vaccine is recommended for control of shingles

A

live attenuated varicella vaccine for adults 60+ whether or not have had shingles

24
Q

What can zoster lead to in immunocompromised patients

A

pneumonia and encephalitis

25
Q

What 4 infectious states does CMV cause

A

asymptomatic
congenital
CMV mononucleosis
reactivation in immunocompromised

26
Q

what can CMV cause if cross placenta

A

congenital disease includeing mental retardation, microcephaly, deafness, seizures, and other birth defects

27
Q

What is CMV mononucleosis

A

young adults
like EBV
“monospot negative mono”

28
Q

What can CMV cause in immunocompromised patients

A

retinitis blindness, pneumonia, disseminated infection and death

29
Q

What occurs with AIDS patients and CMV

A

CMV retinitis

30
Q

What occurs in marrow transplant recipients and CMV infection

A

CMV pneumonitis

31
Q

What part of the blood culture do you look for CMV in

A

in the buffy coat because invades WBC

32
Q

What ways can you Dx CMV

A

buddy coat
Ag detection in blood- only when virus is replicating
PCR- only when virus replicating

33
Q

What is EBV

A

mononucleosis
B cell infection
transforms cells via entering Cd3’
makes huge cells that are pretty much malignant but spontaneous resolutino occurs

34
Q

What cancer is assoc with EBV

A

B cell lymphoma

35
Q

What is at high risk for Patients with Burkitt lymphoma

A

concurrent EBV infection which can lead to death

36
Q

In an immunocompromised host what is at high risk if have EBV infection

A

lymphomas secondary to EBV reactivation

37
Q

What are the symtoms of mono

A

fever, chills, sweats, HA and painful pharyngitis

enlarged lymph nodes and sometimes spleens

38
Q

What does CBC look like for mono infection

A

high WBC with atypical lymphocytes

and heterophile Ab- which is against EBV anc causes agglutination

39
Q

What is the monospot test

A

Looks for heterophile Ab that will cause agglutination of sheep RBC

40
Q

morphology of herpes viruses

A

ds linear DNA enevloped and icosahedral

LAST EXAMMMMMM Year I (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions