Respiratory System Flashcards

1
Q

What is the main function of respiration?

A

supply body with oxygen and dispose of carbon dioxide

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2
Q

Name the 4 main processes of respiration.

A

pulmonary ventilation
external respiration
transport of respiratory gases
internal respiration

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3
Q

define pulmonary respiration (breathing)

A

moving air in and out of lungs

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4
Q

define external respiration

A

has exchange between blood and chambers

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5
Q

define transport of respiratory gases

A

gases must be transported between lungs and tissue cells of the body

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6
Q

how is transport of respiratory gases accomplished?

A

through the cardiovascular system

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7
Q

define internal respiration

A

gas exchanges between blood and tissue cells

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8
Q

Name the main organs of the respiratory system

A
nose
nasal cavity
pharynx
larynx
trachea
bronchi
lungs
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9
Q

which organs make up the upper respiratory tract?

A

nose
nasal cavity
pharynx

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10
Q

which organs make up the lower respiratory tract?

A

larynx
trachea
bronchi
lungs

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11
Q

define respiratory zone

A

site of gas exchange

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12
Q

what makes up the respiratory zone

A

respiratory bronchioles
alveolar ducts
alveoli
microscopic structures

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13
Q

define conducting zone

A

conduits that provide air to reach respiratory zone

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14
Q

what is the main purpose of the conducting zone

A

to warm, humidify, and filter the air

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15
Q

Function of the nose and paranasal sinuses

A
airway for respiration
moistens and warms air
filters air
resonating chamber for speech
houses olfactory receptors
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16
Q

name the main structures that make up the external nose

A
root and bridge
dorsum nasi
apex
philtrum
external nares
alae
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17
Q

_______ divides the nasal cavity

A

nasal septum

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18
Q

it is in the ________ that air enters through the external nares

A

nasal cavity

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19
Q

the nasal cavity is continuous with the…

A

nasal portion of the pharynx

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20
Q

_____ is the cavity superior to the nostrils

A

vestibule

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21
Q

the vestibule contains 2 glands:

A

sebaceous and sweat

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22
Q

the vestibule contains ________ that filter course particles

A

hair follicles

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23
Q

the remaining nasal cavity is lined with __________

A

mucous membrane

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24
Q

name the 2 types of mucous membrane that lines the nasal cavity

A

olfactory mucous

respiratory mucous

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25
Q

what kind of cells make up the respiratory mucous?

A

pseudostratified ciliated columnar epithelium

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26
Q

mucous cells secrete…

A

mucous

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27
Q

serous cells secrete….

A

enzyme laden watery fluid

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28
Q

mucous contain lysozyme which is

A

an antibacterial enzyme

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29
Q

___________ create current that moves mucous toward pharynx

A

ciliated cells

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30
Q

the paranasal sinuses are located in

A

frontal, sphenoid, ethmoid, and maxillary bones

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31
Q

the paranasal sinuses are connected to the nasal cavity by

A

small openings

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32
Q

what does the paranasal sinus produce?

A

mucous that drains into nasal cavity

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33
Q

a function of the paranasal cavity is to

A

warm and moisten air

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34
Q

the pharynx connects

A

mouth and nasal cavity to the larynx and esophagus

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35
Q

the pharynx is a common pathway for

A

food and air

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36
Q

name the 3 regions of the pharynx

A

nasopharynx
oropharynx
laryngopharynx

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37
Q

the nasopharynx only serves as

A

air passage

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38
Q

what happens during swallowing?

A

the uvula closes off nasopharynx to prevent from entering the nasal cavity

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39
Q

where is the opening of the auditory tube (eustachian tube)?

A

nasopharynx

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40
Q

what kind of tissue can be found in the nasopharynx?

A

lymphatic tissue

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41
Q

where exactly is the lymphatic tissue located?

A

pharyngeal tonsils (adenoids)

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42
Q

the ____________ is continuous with the oral cavity

A

oropharynx

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43
Q

define fauces

A

the arched opening at the back of the mouth leading to pharynx

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44
Q

what type of cells is found in the oropharynx

A

more stratified squamous epithelium

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45
Q

why is there stratified squamous epithelium in the oropharynx?

A

to protect against friction damage caused by food

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46
Q

the lymphatic tissue of the oropharynx can be found in the

A

palatine tonsil

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47
Q

the main function of the oropharynx is

A

passage for air and food

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48
Q

the main function of the laryngopharynx is

A

passage for air and food

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49
Q

what kind of cells line the laryngopharynx?

A

stratified squamous epithelium

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50
Q

this lining continues until it reaches

A

the esophagus

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51
Q

the laryngopharynx is _______ the the epiglottis

A

posterior

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52
Q

the laryngopharynx is continuous with what?

A

the esophagus

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53
Q

the extension towards larynx is where

A

respiratory and digestive tracts diverge

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54
Q

how is the laryngopharynx run continuous with the esophagus?

A

when food enters, the air passage is blocked during swallowing

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55
Q

name the functions of the larynx

A

provide an open airway
direct air and food into proper channels
voice production

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56
Q

the larynx is made up of

A

9 cartilages

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57
Q

name the cartilages

A
thyroid (2 fused; laryngeal prominence)
cricoid cartilage
arytenoid cuneiform (3 pairs)
corniculate cartilages (3 pairs)
epiglottis
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58
Q

the epiglottis extends from

A

tongue to anterior edge of thyroid cartilage

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59
Q

during swallowing, the epiglottis is pulled _________

A

superiorly

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60
Q

when the epiglottis is pulled superiorly, it covers

A

laryngeal inlet

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61
Q

the larynx leads to the

A

trachea

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62
Q

the glottis is a

A

laryngeal opening

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63
Q

the glottis is involved in what?

A

speech production

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64
Q

the glottis is made up of

A

vestibular folds

vocal folds

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65
Q

the glottis is surrounded by

A

cuneiform and corniculate cartilage

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66
Q

the trachea descends from…

A

larynx into the mediastinum

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67
Q

the trachea divides into what?

A

2 primary bronchi

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68
Q

name the 3 layers of the tracheal wall.

A

mucosa
submucosa
adventia

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69
Q

the mucosa is covered in what kind of cells?

A

ciliated pseudostratified columnar epithelium

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70
Q

why does it have cilia?

A

to propel particulate materials toward pharynx

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71
Q

the submucosa is a _________ layer

A

connective tissue

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72
Q

the submucosa contains _______ glands that help produce mucous

A

seromucous

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73
Q

the connective tissue is reinforced with what?

A

hyaline cartilage

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74
Q

what does the cartilage do?

A

prevents trachea from collapsing

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75
Q

the primary bronchi enters?

A

lungs

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76
Q

inside lung, the primary bronchi divides into

A

secondary bronchi

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77
Q

how many are on the right?

A

3

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78
Q

how many are on the left?

A

2

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79
Q

each secondary bronchi supplies ___ lung lobe

A

1

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80
Q

there are ____ orders of branching passageways

A

23

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81
Q

define bronchiole

A

air passage less than 1 mm

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82
Q

define terminal bronchiole

A

smallest bronchial

less than 0.5 mm

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83
Q

define respiratory tree

A

collective term for the conduction network with the lungs

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84
Q

as you go further into bronchial tree, hyaline cartilage starts

A

to disappear

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85
Q

cartilage rings are replaced by

A

irregular plates of cartilage

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86
Q

they are ______ in bronchioles

A

absent

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87
Q

name the order that cells change into as the large tube gets smallers

A

pseudostratified columnar
columnar
cuboidal
no cilia or mucus producing cells at and below level of bronchioles

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88
Q

the amount of ___________ increases

A

smooth muscle

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89
Q

an increase in smooth muscle allows for

A

constriction

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90
Q

name the main components of the respiratory zone

A

respiratory bronchioles
alveolar ducts
alveolar sacs
alveoli

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91
Q

alveolar ducts is made up of

A

smooth muscle, elastic and collagen fibers, alveoli

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92
Q

the alveolar ducts terminate into

A

clusters of alveoli

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93
Q

alveolar sacs are groups of

A

alveoli

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94
Q

alveoli are surrounded by

A

elastic fibers

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95
Q

adjacent alveoli are connected via

A

alveolar pores

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96
Q

what do the alveolar pores do

A

equalizes air pressure within lung

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97
Q

what does surfactant do

A

It reduces surface tension of the fluid lining the alveoli allowing alveoli to expand more readily during inspiration.
it breaks water tension so oxygen can move in

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98
Q

______________ cover external surface of alveoli

A

pulmonary capillaries

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99
Q

gas crosses readily by

A

simple diffusion

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100
Q

oxygen goes from alveolus to?

A

capillary

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101
Q

carbon dioxide goes

A

from capillary to alveolus

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102
Q

name the 2 types of cells found in alveoli

A

type I

type II

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103
Q

Type I comprise the

A

alveolar wall

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104
Q

what kind of cells make up type I

A

simple squamous epithelium

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105
Q

Type II cells do what?

A

secrete surfactant

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106
Q

surfactant reduces what?

A

surface tension

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107
Q

which cavity can the lungs be found in?

A

thoracic cavity

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108
Q

each lung is suspended in its own…

A

pleural cavity

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109
Q

name the 4 parts of the lungs

A

root
apex
base
hilus

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110
Q

the root is where

A

bronchial and vascular attachments to mediastinum are

111
Q

the apex is the

A

superior tips

112
Q

the apex is _____ to clavicle

A

deep

113
Q

what is the concave surface lying on top of diaphragm

A

base

114
Q

what is the hilus?

A

indentation through which blood vessels enter and leave

115
Q

what also enters through the hilus?

A

bronchi

116
Q

which lung is the largest lung?

A

right

117
Q

why is the right lung larger?

A

because most of the heart is on the left side of midline

118
Q

how many lobes does right lung have?

A

3

119
Q

the lobes of the right lung are separated by

A

horizontal and oblique fissures

120
Q

how many lobes does the left lung have?

A

2

121
Q

what are the lobes of the left lung separated by?

A

oblique fissure

122
Q

there are ___ segments per lobe

A

10

123
Q

the segments are divided by what?

A

connective tissue septa

124
Q

each segment is serviced by what?

A

its own artery and vein and receives from an unique bronchus

125
Q

what is a lobule?

A

subdivision of lung that is smaller than a segment

126
Q

what is serviced to a lobule

A

a large bronchiole and its branches

127
Q

name the 2 circulations of the lungs

A

pulmonary and bronchial

128
Q

what does pulmonary circuit do?

A

delivers oxygen poor blood from heart and returns oxygen rich blood to heart

129
Q

what does bronchial circuit do?

A

provide system blood to lung tissue

130
Q

define pleura

A

the serous membrane investing the lungs and lining the thoracic cavity, completely enclosing a potential space known as the pleural cavity

131
Q

name the 2 layers of the pleura

A

parietal pleura

visceral pleura

132
Q

the parietal pleura covers what?

A

exterior surface

lines thoracic wall and superior diaphragm

133
Q

the visceral pleura covers what?

A

external surface of lung

134
Q

what is the space between the layers fluid filled?

A

it permits membranes to slide during respiration and it prevents separation from wall of thorax

135
Q

name the 2 phases of pulmonary ventilation

A

inspiration

expiration

136
Q

expiration is

A

the relaxation of intercostal muscles and abdominal muscles, this causes the diaphragm to relax

137
Q

inspiration is

A

when muscles contract, causing expansion of thorax, elevating ribs and moving the sternum, the diaphragm contracts increasing the superior-inferior dimension of the thoracic cavity.

138
Q

define atmospheric pressure

A

pressure exerted by gases around body

139
Q

what is described relative to atmospheric pressure?

A

respiratory pressure

140
Q

negative pressure indicates

A

pressure is lower relative to atmospheric pressure

141
Q

positive pressure indicates

A

pressure is greater relative to atmospheric pressure

142
Q

what is intrapulmonary pressure?

A

pressure within alveoli

143
Q

what changes intrapulmonary pressure?

A

phases of breathing

144
Q

ultimately ________ is equalized with atmospheric pressure

A

intrapulmonary pressure

145
Q

what is always negative relative to both intrapulmonary and atmospheric pressures

A

intrapleural pressure

146
Q

intrapleural pressure __________ with phases of breathin

A

fluctuates

147
Q

the amount of pleural fluid must be

A

at a minimum to lose surface tension

148
Q

name the 2 forces that pull lungs away from thorax wall

A

elasticity of lungs favor smallest dimension

surface tension of alveolar fluid

149
Q

what is the force that pulls lungs toward thorax wall?

A

elasticity of chest wall

150
Q

forces pulling lungs away from thorax wall and the force that pulls lungs toward thorax wall result in

A

negative intrapleural pressure

151
Q

define transpulmonary pressure

A

difference between intrapulmonary and intrapleural pressures

152
Q

transpulmonary pressure does what?

A

keeps lungs from collapsing

153
Q

the serous fluid will always be

A

more (always) negative than the outside environment

154
Q

volume changes leads to

A

pressure changes

155
Q

inspiration is a ______ process

A

active

156
Q

inspiration depends on what?

A

decreasing pressure in lungs

157
Q

how is inspiration achieved?

A

by increasing lung volume, the inspiratory muscles do this

158
Q

name the inspiratory muscles

A

diaphragm

external intercostal muscles

159
Q

quiet inhalation occurs when the diaphragm

A

constricts (moves inferiorly and flattens)

160
Q

when the diaphragm constricts, the volume

A

increases

161
Q

what doe the external intercostal muscles do?

A

lift the rib cage and pull sternum forward

162
Q

as a result, thoracic diameter increases…

A

laterally and anteroposteriorly

163
Q

Also, the intrapulmonary volume _______ and pressure __________ during inhalation

A

increases

decrease

164
Q

when intrapulmonary volume increases and pressure decreases, air

A

rushes into lungs along pressure gradient

165
Q

intrapleural pressure ___________ relative to atmospheric pressure

A

declines

166
Q

as inhalation ends, intrapulmonary and atmospheric pressures are

A

equal

167
Q

deep (forced) inhalation uses

A

accessory muscles to further increase thoracic volume

168
Q

name the accessory muscles used

A

scalenes and sternocleidomastoid muscles of neck
pectoralis muscles of chest
erector spinae of back

169
Q

expiration is a ______ process

A

passive

170
Q

during expiration, the inspiratory muscles do what?

A

relax

171
Q

during expiration the rib cage

A

descends

172
Q

during expiration the lungs

A

recoil

173
Q

during expiration, the intrapulmonary volume

A

decreases

174
Q

in expiration, alveoli

A

compress

175
Q

this allows the pressure to

A

rise within alveoli above atmospheric pressure

176
Q

with the pressure rising, air

A

moves along pressure gradient out of lungs

177
Q

during forced expiration, the abdominal wall muscles

A

contract

178
Q

the contraction of the abdominal wall muscles allow

A

increase in abdominal cavity pressure

179
Q

the increase in abdominal cavity pressure forces what?

A

abdominal organs superiorly against diaphragm

180
Q

during forced expiration, the rib cage

A

depresses

181
Q

name the other 2 muscles that can depress rib cage and decrease thoracic volume

A

internal intercostal muscles

latissimus dorsi

182
Q

name the 3 main factors that affect pulmonary ventilation

A

airway resistance
alveolar surface tension
lung compliance

183
Q

airway resistance is caused by

A

friction

184
Q

resistance is determined by

A

diameters of conducting tubes

185
Q

resistance does not contribute to what?

A

significantly to ventilation

186
Q

there is no flow where friction is

A

greatest

187
Q

in what kind of tubes is the flow greatest?

A

large

188
Q

name the pathological constriction cause of airway resistance

A

asthma

189
Q

describe surface tension

A

at liquid-gas boundaries, molecules of the liquid are more strongly attracted to each other than to the gaseous molecules

190
Q

why are liquid molecules drawn together?

A

to reduce contact with dissimilar gas molecules

191
Q

without surfactant, surface tension would cause

A

alveoli to collapse between breaths

192
Q

name the benefits of surfactant

A

reduces surface tension of alveolar fluid

less energy is needed to expand lungs

193
Q

define lung compliance

A

measure of lung distensibility (expandability)

194
Q

what does great compliance allow?

A

greater ease to expand

195
Q

name the factors that affect lung compliance

A

elasticity of lung tissue and thoracic cage

surface tension of alveoli

196
Q

describe the factors that favor compliance

A

elasticity is high and surface tension is low

197
Q

name the 4 factors that diminish compliance

A

reduced lung resilience
blocked respiratory passages
reduced production of surfactant
decreased thoracic cage flexibility

198
Q

name the 4 types of respiratory volumes

A

tidal
inspiratory reserve
expiratory reserve
residual volumes

199
Q

define tidal volume

A

volume of air moving into lungs during quiet breathing

200
Q

define inspiratory reserve volume

A

amount of air that can be forcibly inspired beyond tidal volume

201
Q

define expiratory reserve volume

A

amount of air that can be exhaled after a tidal volume

202
Q

define residual volume

A

amount of air remaining after maximum voluntary expiration

203
Q

residual volume is needed why?

A

to keep alveoli inflated

204
Q

name the 4 respiratory capacities

A

inspiratory capacity
functional residual capacity
vital capacity
total lung capacity

205
Q

define inspiratory capacity

A

amount of air that can be inspired after tidal expiration

sum of tidal and inspiratory reserve volumes

206
Q

define functional residual capacity

A

sum of residual and expiratory reserve volume

207
Q

define vital capacity

A

total amount of exchangeable air

sum of total, inspiratory reserve, and expiratory reserve

208
Q

vital capacity makes up ____ of total lung capacity

A

80%

209
Q

define total lung capacity

A

sum of all lung volumes

sum of total, inspiratory reserve, expiratory reserve, and residual volume

210
Q

define anatomical dead space

A

air in conducting zone that never contributes to gas exchange in alveoli
is about 150 ml

211
Q

define total ventilation

A

total amount of air that flows into or out of the respiratory tract in 1 minute

212
Q

define forced vital capacity

A

maximum amount of gas forcibly expired following a deep breath

213
Q

define dalton’s law of partial pressure

A

total pressure exerted by a mixture of gases is equal to the sum of the individual pressures exerted by each gas

214
Q

the sum of partial pressure is equal to

A

total pressure of gas mixture

215
Q

direction of movement is dependent on

A

the partial pressure in the 2 phases

216
Q

describe alveolar gas composition

A

more CO2 and H2O

less O2 than atmosphere

217
Q

this kind of difference reflects

A

gas exchange at lungs (CO2 out and O2 in)

218
Q

during external respiration,

A

oxygen enters and carbon dioxide leaves the blood

219
Q

external respiration occurs across

A

the respiratory membrane

220
Q

oxygen diffuses readily from

A

blood into tissue

221
Q

carbon dioxide readily diffuses from

A

tissues into blood

222
Q

name 3 factors affecting the movement of oxygen and carbon dioxide

A

partial pressure gradients and gas solubility
structure of respiratory membrane
functional aspects

223
Q

oxygen as a ______________ partial pressure gradient than carbon dioxide

A

steeper

224
Q

the thickness of respiratory membrane affects

A

rate of diffusion

225
Q

so in a pathological condition, exchange may be slowed by

A

thickening of the respiratory membrane

226
Q

in healthy lungs, surface area is

A

immense

227
Q

disease may do what to surface area in lungs?

A

reduce it

228
Q

for gas exchange to be efficient…

A

perfusion of pulmonary capillaries must match alveolar conditions

229
Q

if alveolar ventilation is inadequate, terminal arterioles…

A

constrict to redirect blood flow to more highly ventilated areas

230
Q

if alveoli are maximally ventilated, pulmonary arterioles…

A

dilate to increase blood flow into the more highly ventilated area

231
Q

brochiole diameter _______ CO2 levels

A

parallels

232
Q

poor alveolar ventilation results in

A

low PO2 and high PCO2

233
Q

low PO2 and high PCO2 causes

A

bronchioles dilate

terminal arterioles constrict

234
Q

increased alveolar ventilation results in

A

high PO2 and low PCO2

235
Q

high PO2 and low PCO2 causes

A

bronchioles constrict

terminal arterioles dilate

236
Q

in internal respiration, oxygen

A

diffuses readily from blood into tissue and carbon dioxide readily diffuses from tissue into blood

237
Q

what are the two ways oxygen is transported?

A

Hemoglobin

dissolved in plasma

238
Q

which is the primary mechanism of transporting oxygen though?

A

hemoglobin

239
Q

define oxyhemoglobin (HbO2)

A

oxygen bond to hemoglobin

240
Q

define deoxyhemoglobin (HHb)

A

hemoglobin that has released its oxygen

241
Q

what does it mean by “partially saturated” hemoglobin?

A

less than 4 hemoglobin hemes bound to oxygen

242
Q

what does it mean by “fully saturated” hemoglobin?

A

all 4 hemoglobin hemes bound to oxygen

243
Q

affinity _____ as oxygen is serially added to 4 hemoglobin polypeptide chains

A

increases

244
Q

after initial oxygen molecule is bound, __________ is enhanced

A

infinity for oxygen

245
Q

affinity decreases as oxygen…

A

is released by hemoglobin

246
Q

name the 5 factors that affect shape and affinity of hemoglobin to oxygen

A
PO2
Temperature
Blood pH
PCO2
BPG
247
Q

hemoglobin is more present in ___

A

lungs

248
Q

arterial blood is __ saturated

A

98%

249
Q

blood loses 25% of its oxygen in _______

A

capillary beds

250
Q

with an increased in metabolic activity, oxygen is

A

more readily dissociated

251
Q

nitrous oxide is a vaso________

A

dilator

252
Q

_________ offsets the effect of NO

A

hemoglobin

253
Q

define hypoxia

A

inadequate oxygen delivery to body tissues

254
Q

anemic hypoxia results from a

A

reduced RBC number and an abnormal or reduced amount of hemoglobin

255
Q

define ischemic hypoxia

A

impaired or blocked blood flow

256
Q

congestive heart failure results from

A

body-wide ischemia

257
Q

an embolism or thrombosis results from

A

local interruption in blood flow

258
Q

what is it when you have histotoxic hypoxia

A

adequate delivery but tissues are unable to use oxygen because of metabolic toxins

259
Q

define hypoxemic hypoxia

A

reduced arterial PO2

260
Q

___ is more readily bound by heme than oxygen

A

CO

261
Q

name the 3 forms CO2 can be transported in blodd

A
  1. dissolved in plasma
  2. bound to hemoglobin in RBCs
  3. as bicarbonate ion in plasma
262
Q

CO2 does not compete with oxygen when it binds to hemoglobin because

A

CO1 binds to globin part

263
Q

most CO2 is converted to

A

bicarbonate ion (HCO3-)

264
Q

the more CO2 there is in blood, the more bicarbonate, which means that blood has a

A

low pH

265
Q

bicarbonate ion rapidly diffuses out of the RBCs into the plasma and carried to

A

lungs

266
Q

what happens to bicarbonate ions in lungs?

A

converted bact to CO2 and enters RBCs and CO2 diffuses from blood into alveoli

267
Q

The Medulla respiratory centers consists of

A

Dorsal respiratory group (DRG)

Ventral respiratory group (VRG)

268
Q

the DRG is a _____________________ center

A

pacesetting respiratory center

269
Q

Neural activity in DRG activates…

A

intercostal muscles and diaphragm (inspiration)

270
Q

Expiration is a ____ phase

A

passive

271
Q

the VRG regulates

A

internal intercostals

compresses rib cage

272
Q

the VRG is responsible for a

A

forced expiration

273
Q

what does the Pons respiratory center do?

A

inhibition of medulla