Respiratory Physiology - Pulmonary Blood Flow Flashcards

1
Q

The pressure on the R heart is greater or less than the L heart

A

Greater

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2
Q

Both sides of the heart pump how much blood

A

The same

50 ml

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3
Q

What is the systolic pressure of the LV and RV

A
LV = 120 mmHg 
RV = 25 mmHg
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4
Q

What is the diastolic pressure in the ventricles and what does this mean

A

0 mmHg

Blood does not flow back in passively

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5
Q

What is the pressure for the LA and RA and what does this mean

A

15/4 - slight diastolic pressure which means blood comes in passively

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6
Q

What is the typical CO at rest

A

5 Lpm

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7
Q

When the heart begins to fail, where does the blood back up

A

The lungs

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8
Q

What is the pressure of the Ao and PA

A

Ao - 120/80

PA - 25/15

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9
Q

Extra-alveolar capillaries receive blood from where

A

The LV

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10
Q

What is the role of the extra-alveolar capillaries

A

Deliver O2 to the tissue of the lungs

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11
Q

What doe the extra-alveolar capillaries feed back into

A

The pulmonary veins

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12
Q

What is the PaO2 in the artery of the alv. And extra-alv. Capillaries respectively

A

Alv. - low

Extra-alv. - high

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13
Q

What is the O2 in the venous return to the PV in the alv. And extra-alv. Capillaries respectively

A

Alv. - high O2

Extra alv. - low O2

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14
Q

What is the equation for Pulmonary BP

A

PBP = CO x PVR

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15
Q

Pulmonary vascular resistance is higher or lower than in the periphery? And what does this mean

A

Lower, this means we can move more blood across the lungs to get them oxygenated and supply the body

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16
Q

What is the main thing that determines PVR

A

How many alveoli are open at any given moment in time

17
Q

What happens during exercise in the PVR and why does this happen and what does it allow?

A

PVR drops because more alveoli are open

This allows the lungs to accommodate the increased CO and allow for more oxygenation of RBCs

18
Q

The blood pressure in the lungs is higher or lower in the apex (zone I) of the heart? What about the blood flow and the alveoli?

A

The blood pressure is lower, yet the alveoli are more expanded

Blood flow is less

19
Q

The blood pressure in the lungs is higher or lower in zone II of the heart? What about the blood flow and the alveoli?

A

The blood pressure is about the same as the heart with a normal blood flow

The alveoli are average in size

20
Q

The blood pressure in the lungs is higher or lower in the base (zone III) of the heart? What about the blood flow and the alveoli?

A

The blood pressure is highest due to being below the heart

The alveoli are smaller

The blood flow is greatest here

21
Q

What does NO do and what produces it?

A

Made by the vascular endothelium

Causes smooth muscle relaxation and vasodilation during normal pulmonary blood flow

22
Q

If the alveolie are “dry” what can better happen

A

O2 can move easier across capillaries into the alveoli

23
Q

What is the capillary hydrostatic pressure

A

Blood pressure in the capillary, contributes most to starling forces

Is trying to push fluid into the alveoli

24
Q

What is the tissue hydrostatic pressure and what role does it play in the starling forces

A

Pressure in the tissue which SHOULD push fluid into the capillary, HOWEVER since the intrapleural cavity is NEGATIVE, the Pt actually helps push fluid into the alveoli

25
What is the plasma oncotic pressure
This is the capillary oncotic pressure | It tries to pull water into the capillary
26
What is the tissue oncotic pressure
Tries to pull water into the alveolus
27
So in the lung, what is the only force moving water from alveoli to capillary
Tissue oncotic pressure
28
Equation for starling forces
(Pc + Pi[tissue] + Ptissue) - pi[capillary]
29
Starling Forces favor the movement of water into the alveoli. This is bad, so how do we fix it?
The lymphatics! Drain excess filtrate from lungs away to the vessels