Respiratory Physiology - Pulmonary Blood Flow Flashcards

1
Q

The pressure on the R heart is greater or less than the L heart

A

Greater

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2
Q

Both sides of the heart pump how much blood

A

The same

50 ml

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3
Q

What is the systolic pressure of the LV and RV

A
LV = 120 mmHg 
RV = 25 mmHg
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4
Q

What is the diastolic pressure in the ventricles and what does this mean

A

0 mmHg

Blood does not flow back in passively

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5
Q

What is the pressure for the LA and RA and what does this mean

A

15/4 - slight diastolic pressure which means blood comes in passively

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6
Q

What is the typical CO at rest

A

5 Lpm

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7
Q

When the heart begins to fail, where does the blood back up

A

The lungs

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8
Q

What is the pressure of the Ao and PA

A

Ao - 120/80

PA - 25/15

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9
Q

Extra-alveolar capillaries receive blood from where

A

The LV

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10
Q

What is the role of the extra-alveolar capillaries

A

Deliver O2 to the tissue of the lungs

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11
Q

What doe the extra-alveolar capillaries feed back into

A

The pulmonary veins

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12
Q

What is the PaO2 in the artery of the alv. And extra-alv. Capillaries respectively

A

Alv. - low

Extra-alv. - high

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13
Q

What is the O2 in the venous return to the PV in the alv. And extra-alv. Capillaries respectively

A

Alv. - high O2

Extra alv. - low O2

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14
Q

What is the equation for Pulmonary BP

A

PBP = CO x PVR

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15
Q

Pulmonary vascular resistance is higher or lower than in the periphery? And what does this mean

A

Lower, this means we can move more blood across the lungs to get them oxygenated and supply the body

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16
Q

What is the main thing that determines PVR

A

How many alveoli are open at any given moment in time

17
Q

What happens during exercise in the PVR and why does this happen and what does it allow?

A

PVR drops because more alveoli are open

This allows the lungs to accommodate the increased CO and allow for more oxygenation of RBCs

18
Q

The blood pressure in the lungs is higher or lower in the apex (zone I) of the heart? What about the blood flow and the alveoli?

A

The blood pressure is lower, yet the alveoli are more expanded

Blood flow is less

19
Q

The blood pressure in the lungs is higher or lower in zone II of the heart? What about the blood flow and the alveoli?

A

The blood pressure is about the same as the heart with a normal blood flow

The alveoli are average in size

20
Q

The blood pressure in the lungs is higher or lower in the base (zone III) of the heart? What about the blood flow and the alveoli?

A

The blood pressure is highest due to being below the heart

The alveoli are smaller

The blood flow is greatest here

21
Q

What does NO do and what produces it?

A

Made by the vascular endothelium

Causes smooth muscle relaxation and vasodilation during normal pulmonary blood flow

22
Q

If the alveolie are “dry” what can better happen

A

O2 can move easier across capillaries into the alveoli

23
Q

What is the capillary hydrostatic pressure

A

Blood pressure in the capillary, contributes most to starling forces

Is trying to push fluid into the alveoli

24
Q

What is the tissue hydrostatic pressure and what role does it play in the starling forces

A

Pressure in the tissue which SHOULD push fluid into the capillary, HOWEVER since the intrapleural cavity is NEGATIVE, the Pt actually helps push fluid into the alveoli

25
Q

What is the plasma oncotic pressure

A

This is the capillary oncotic pressure

It tries to pull water into the capillary

26
Q

What is the tissue oncotic pressure

A

Tries to pull water into the alveolus

27
Q

So in the lung, what is the only force moving water from alveoli to capillary

A

Tissue oncotic pressure

28
Q

Equation for starling forces

A

(Pc + Pi[tissue] + Ptissue) - pi[capillary]

29
Q

Starling Forces favor the movement of water into the alveoli. This is bad, so how do we fix it?

A

The lymphatics! Drain excess filtrate from lungs away to the vessels