Gas Transport

Question 1

What is the PAO2 of the environment

Answer 1

150 mmHg

Question 2

What is the PaO2 and PaCO2 of Arterial blood

Answer 2

O2 - 95 mmHg

CO2 - 40 mmHg

Question 3

What is the PaO2 and PaCO2@ of venous blood

Answer 3

O2 - 40 mmHg

CO2 - 45 mmHG

Question 4

What is the soluablitity of dissolved O2 in the blood

Answer 4

0.3ml/dl of blood/100 mmHg

Not enough to meet metabolic needs

Question 5

How much O2 and CO2 respectively are moved in and out of lungs a minute

Answer 5

250 ml O2

200 ml CO2

Question 6

The amount of dissolved O2 in the blood (PaO2) is in equilibrium with what

Answer 6

The O2 on hemoglobin

Question 7

Any PO2 > 60 mmHb, what is O2 sat.?

Answer 7

Atleast 85%

Question 8

Hb allows how much O2 to be delivered per dl of blood

Answer 8

17ml

Question 9

What does a L shift indicate

Answer 9

An increased affinity of Hb for O2 (in the lungs)

Question 10

What does a R shift represent

Answer 10

A decrease in affinity of Hb for O2

Question 11

What happens to the oxygen Hb curve during working out

Answer 11

L shift in lungs, but a R shift in tissues (Good)

Question 12

High CO2 and low pH do what to the curve

What about low Co2 and high pH

Answer 12

RS

LS

Question 13

High CO2, temp, and 2,3 DPG are found where? What does this mean for the curve

Answer 13

Found in tissues, this means there is a RS which is good, allows for tissues to receive oxygen from Hb

Question 14

What is the O2 content of venous blood

Answer 14

15 ml O2/dl blood

Question 15

Define the a-v O2 difference (equation)

Answer 15

PaO2 - PVo2

Represents how much Oxygen was used by the tissue

Comes top 4.6 in a healthy individual

Question 16

RQ for carbs, FFA, and mixed

Answer 16

Carbs - 1
FFA - 0.7
Mix - 0.8 (normal)

Question 17

Define respiratory quotient and give the equation

Answer 17

The ration between Co2 produced and the O2 consumed

RQ = Vdot CO2/Vdot O2

Question 18

What is the solubility of CO2

Answer 18

20x that of O2

6ml O2/dl blood/100 mmHg

Question 19

There is about how much CO2 dissolved in each Dl of blood

Answer 19

2.7 ml CO2

Question 20

What is the main carrier of CO2 from the blood to the alveoli

Answer 20

HCO3

Question 21

What enzyme facilitates the change of H2CO3 into HCO3

Answer 21

Carbonic anhydrase

Question 22

Define the chloride shift and its clinical signifance

Answer 22

Cl shifts into cells which allows for HCO3 to leave cells

So less Cl will not allow for adequate HCO3 transport and this more CO2 in blood and lower pH (acidic)

Question 23

How does dissolved CO2 travel in the lungs

Answer 23

Down its concentration gradient

Question 24

How does the movement of dissolved CO2 in the alv. Capillaries facilitate movement of CO2 from HCO3

Answer 24

Dissolved CO2 moves down concentration gradient which decreases the CO2 in the alv. Cap. This causes CO2 in the equation to drop and thus HCO3 is converted back into CO2 and H2O (moving the reaction backward)