respiratory phys Flashcards

1
Q

what is the key factor that controls respiration?

A
  1. incr partial pressure of CO2
  2. reduction in PO2
  3. reduction in pH
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2
Q

which factor can directly stimulate the peripheral chemoreceptors and the central chemoreceptors?

A

PCO2

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3
Q

is there cartilage in bronchi or in bronchioles?

A
bronchi = cartilage
bronchioles = no cartilage
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4
Q

what drives resistance to airflow?

A

smooth muscle in bronchus and bronchiole

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5
Q

common obstructive diseases that increase resistance to air flow (4)

A
  1. bronchitis
  2. asthma
  3. tumors
  4. aspiration
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6
Q

what are obstructive conditions in the airway wall?

A
  1. asthma
  2. acute bronchitis
  3. chronic bronchitis
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7
Q

what are obstructive conditions related to loss of lung parenchyma?

A

emphysema

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8
Q

what are obstructive conditions in the airway lumen?

A
  1. bronchiectasis
  2. bronchiolitis
  3. CF
  4. acute tracheobronchial obstruction
  5. epiglottis
  6. croup
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9
Q

what cells produce collagen and elastin?

A

fibroblasts

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10
Q

collagen and elastin is responsible for what?

A

distensibility and elastic recoil of lungs

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11
Q

what are the exit points for pleural liquid, proteins, and cells to be removed from pleural space?

A

stomata

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12
Q

pleural effusion is most commonly seen with?

A

CHF

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13
Q

restrictive or obstructive? the result of decreased expansion of the lungs due to alterations in lung parenchyma, pleura, chest wall or neuromuscular fxn?

A

restrictive pulm disorders

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14
Q

when you expand your chest, the pressure incr or decr?

A

decr

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15
Q

more collagen ____compliance

A

decr

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16
Q

would pneumonia incr or decr compliance?

A

decr

17
Q

compliance is the ________of elasticity

A

inverse

18
Q

what is the largest vascular bed?

A

pulmonary circulation

19
Q

is pulm circulation or systemic more compliant?

A

pulm circulation

20
Q

what part of the pulm circulation creates a physiological shunt?

A

bronchial circualtion

21
Q

what is the mechanism for automatic control of pulm blood flow distribution?

A

hypoxic pulmonary vasoconstriction (HPV)

22
Q

alveolar hypoxia results in vasodilation or vasoconstriction?

A

vasoconstriction

23
Q

what is the optimal V/Q ratio?

A

0.8

24
Q

which type of volume cannot be measured by spirometry?

A

residual volume

25
Q

FEV1/FVC under 0.7?

A

obstructive lung disease

26
Q

FEV1/FVC >0.8

A

restrictive lung disease

27
Q

if you have a lot of collagen in lung interstitium (more than elastin)?

A

lung will collapse a lot easier than distend

28
Q

if lose elastin in lung interstitium?

A

loss of elastic recoil

29
Q

is CO2 or O2 more soluble?

A

CO2

30
Q

CHF rsults in ____pulmonary venous hydrostatic pressure from the ____side

A

incr, visceral

31
Q

in pleural effusion, there is _____microvascular oncotic pressure

A

decr

32
Q

the extent to which the lungs will expand for each unit incr in transpulmonary pressure

A

lung compliance

33
Q

more collagen - compliance goes up or down?

A

compliance goes down

34
Q

does pneumonia incr or decr compliance?

A

decr compliance (limit ability of lung to expand)