Respiratory Non-Neoplastic Flashcards

1
Q

What is an infection of the upper airways?

A

Acute inflammatory process, affecting mucous membranes of the respiratory tract

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2
Q

What are some infections of the upper airways?

A

Rhinitis, laryngitis, tonsillitis, sinusitis

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3
Q

What are the symptoms of upper airway infections?

A

Malaise, headache, sore throat, discharge

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4
Q

What is an infection of the lower airways (Pneumonia)?

A

Inflammation of the lung parenchyma

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5
Q

What are the causes of lower airway infections (Pneumonia)?

A

Infectious agents inhaled causes chest wall trauma

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6
Q

What are the categories of different pneumonia ?

A

Community, hospital, aspiration

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7
Q

What are the clinical features of Pneumonia?

A

Fever, rigours, SOB, chest pain, purulent sputum, cough

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8
Q

What is the morphology of Pneumonia?

A

Lobar (one lobe), bronchopneumonia( both), interstitial

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9
Q

What is community acquired Pneumonia?

A

Common - especially in elderly

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10
Q

What is the bacteria involved in community Pneumonia?

A

Strep. pneumoniae, staph aureus

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11
Q

Is community acquired Pneumonia lobar or bronchopneumonia?

A

Can be both

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12
Q

What is hospital acquired Pneumonia?

A

Any Pneumonia at least 48-72 hours after admission

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13
Q

What is the bacteria involved in hospital Pneumonia?

A

Gram neg bacilli and staph aureus

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14
Q

Why is hospital acquired Pneumonia serious?

A

As is can be fatal - most common cause of death in ICU

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15
Q

What are the symptoms of Pneumonia?

A

Fever, increased WBC, cough with sputum, chest x-ray

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16
Q

What is aspiration Pneumonia?

A

Inhalation of foreign material

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17
Q

Who is at risk of developing aspiration Pneumonia?

A

Elderly, stroke, dementia, anaesthetic

18
Q

What lobes does aspiration Pneumonia effect?

A

Right middle and right lower

19
Q

What is an obstructive disease?

A

Partial or complete obstruction

20
Q

What is an restrictive disease

A

Decreased lung capacity

21
Q

What are some obstructive diseases?

A

Asthma, COPD, bronchiectasis

22
Q

What is COPD emphysema?

A

Irreversible enlargement of the airspaces distal to the terminal bronchiole, related strongly to smoking

23
Q

What is the pathogenesis of COPD emphysema?

A

Chronic inflammation throughout airways, imbalance of oxidants and antioxidants

24
Q

What are the clinical symptoms of COPD emphysema?

A

Dyspnoea, cough, weezing, weight loss

25
What is COPD chronic bronchitis?
Persistent cough with sputum for over 2 years, 3 months per year
26
What could be the cause of COPD bronchitis?
Long standing irritation - smoking Hypertropy Mucus in small airways
27
What is the morphology of COPD chronic bronchitis?
Mucus membrane swelling, mucus, and mucus plugging
28
What is asthma?
Chronic inflammatory disorder of airways
29
What are the signs and symptoms of asthma?
Wheezing, breathlessness, chest tightness, cough
30
What is the morphology of Asthma?
Lung over inflation, thick mucus plugs, airway remodelling
31
What is bronchiectasis?
Permanent destruction and dilation of the airways
32
What is the morphology of bronchiectasis?
Dilated, inflamed airways
33
What is a pulmonary embolism?
Blockage of a main or branch pulmonary artery by an embolus
34
What are the usual source of emboli?
Deep venous thrombi (95%)
35
What are the clinical signs of PE?
Chest pain, SOB, hypoxia, sudden death
36
What is pulmonary oedema?
Accumulation of fluid in the air spaces and parenchyma of the lung
37
What is the morphology of pulmonary oedema?
Fluid in basal regions, engorged alveolar capillaries, heavy wet lungs
38
What are the clinical signs of pulmonary oedema?
SOB, pink frothy sputum, CXR findings
39
What are the Type1 - Hypoxia with normal or low PCO2?
Pneumonia, PE, asthma, pulmonary oedema, pulmonary fibrosis
40
What are the Type11-Hypoxia with high PCO2?
Asthma, COPD, reduced resp drive, neuromuscular disease, thoracic wall disease