Disorders of Growth 1 and 2 Flashcards

1
Q

What is a neoplasm?

A

Abnormal mass of tissue

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2
Q

What is neoplasia?

A

Neoplasm formed

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3
Q

What is the difference between benign and malignant tumours?

A

Benign - pushes other tissues

Malignant - invades other tissues and can mets

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4
Q

How do malignant tumours spread?

A

Local/ direct

Lymphatic, blood, transcoelmic, epithelium

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5
Q

What is the benign name

What is the malignant name

A

Benign - oma

Malignant - sarcoma

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6
Q

What is Leukaemia

A

Neoplastic proliferation of stem cells

Neoplastic calls spill over into blood stream

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7
Q

What is lymphoma ?

A

Lymphoid tissue cell proliferation

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8
Q

What is Hodgkin’s disease?

A

Mix of cells including reed

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9
Q

What is Non-Hodgkin’s lymphoma?

A

Lacks cellular mix

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10
Q

What is teratoma?

A

From totipotential cells, producing tissues .. Teeth hair

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11
Q

What are the precursors of malignant rumours?

A

Lesions with an increased risk of invasive tumour

Can be non-neoplastic and neoplastic

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12
Q

What are the non-neoplastic examples?

A

Chronic inflammation, cirrhosis of the liver, chronic ulcerative colitis, xeroderma pigmentosum

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13
Q

What is chronic inflammation non-neoplastic?

A

Varicose leg ulcers leading to skin cancer

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14
Q

What is cirrhosis of the liver non-neoplastic?

A

Hepatocellular carcinoma

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15
Q

What is chronic ulcerative colitis non-neoplastic?

A

Large intestine adenocarcinoma

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16
Q

What is xeroderma pigmentosum non-neoplastic ?

A

Squamous cell carcinoma skin

17
Q

What is familiar polyposis coli neoplasia ?

A

Autosomal dominant, 1000 adenoma of large intestine, carcinoma inevitable

18
Q

What is intra-epithelial neoplasia?

A

Nuclear changed of carcinoma without breaching basement membrane - “dysplasia”

19
Q

What are some effects of malignant tumours ?

A

All the physical activities of benign, tissue destruction, secondary infection

20
Q

What is cachexia?

A

Severe weight loss from increased metabolic rate - associated with malignant tumours