Respiratory Histology Flashcards
What are the three regions of the nasal cavity?
Nasal Vestibule (just inside the nostrils - lined with skin)
Respiratory region (inferior 2/3 of the nasal cavities)
Olfactory region (upper 1/3)
What differentiates olfactory mucosa from respiratory mucosa?
Thicker
Lack of goblet cells
What is the function of sustentacular cells?
Mechanical and metabolic support to olfactory receptor cells.
At what respiratory division do goblet cells stop being produced?
Broncioles (they do not have goblet cells)
In what layer of the trachea do we find the trachealis muscle?
The adventitia
What respiratory division do inhalers affect?
Why?
Bronchioles
Because of their prominent smooth muscle
At what point in the respiratory division do we see club cells and simple cuboidal epithelium?
Terminal Bronchioles
What is the function of club cells?
Secrete lipoprotein to prevent airway collapse during expiration
What is the function of the conducting portion of the lung?
What is the function of the respiratory portion of the lung?
1) Warms, filters and humidifies air
2) Pass air to alveoli for gas exchange
Where does the conducting portion start and end?
What are the parts of the respiratory portion?
1) Starts at nasal cavity and ends at terminal bronchioles
2) Respiratory bronchioles, alveolar ducts, alveolar sacs
What type of epithelium are the true vocal folds/cords lined with?
Nonkeratinized stratified squamous
What is classified as respiratory epithelium?
Pseudostratified ciliated columnar
What are modified columnar epithelial cells that synthesize and secrete mucus?
Goblet cells
What structure do we stop seeing club cells?
What structure do we stop seeing elastic fibers?
What structure do we stop seeing ciliated cells?
What structure do we stop seeing goblet cells?
Glands are found in all of the respiratory tract except?
1) Alveolar ducts
2) Throughout but increases as we get more distal
3) Respiratory bronchioles
4) Become less numerous as we get more distal
5) Bronchioles
What type of epithelium lines alveolar ducts, rings, and sacs?
Simple squamous
What cell type are type I pneumocytes?
Type II?
1) Squamous (flat)
2) Cuboidal (rounded)
What does type I pneumocytes create surface for?
What is the role of type II pneumocytes?
1) Gas exchange
2) Secrete surfactant
What is vitally important for an infant to produce in order to survive?
Why?
1) Surfactant
2) Reduces surface tension within alveoli to prevent collapse during respiration
With emphysema there is a chronic obstruction of airflow due to?
This is accompanied by?
What is it caused by?
1) Narrowing of bronchioles
2) Destruction of alveolar walls
3) Smoking
What is pneumonia?
The air spaces are filled with exudate containing?
How does it affect the capillaries in the lung?
During acute pneumonia the lungs undergo a red hepatization stage where it looks like?
1) Inflammation of lung tissue
2) Neutrophils, RBCs, and Fibrin
3) Enlarges them and congested with RBCs
4) Liver

Clara cells

Trachea

A) Type I pneumocyte
B) Endothelial cells
C) Basement membrane
D) Blood of capillary
E) Lumen of alveollus

1) Pseudostratified columnar ciliated epithelium
2) Ciliated columnar epithelial cells, goblet cells, stem cells
3) Synthesize and secrete mucus
4) Release mucigen granules by exocytosis and combine with water
5) Trachea, bronchi, nasal cavity










