Circulation and Hemodynamics Flashcards

1
Q

Rank the following vessels from highest pressure to lowest: Arteries, Veins, Arterioles

A

1) Arteries
2) Arterioles
3) Veins

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2
Q

What feature of arterioles can control blood flow by changing resistance?

A

Contraction of smooth muscle walls

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3
Q

What is a large cross-sectional area of vessels with a single endothelial lining?
What goes on at this location?

A

1) Capillaries

2) Nutrient, waste, and gas exchange

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4
Q

Veins can contract to move blood to?

Why?

A

Arterial side in order to increase BP

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5
Q

What is the equation for blood flow?

A

Q (flow) = ΔP (pressure gradient) / R (resistance)

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6
Q

What is the important variable in poiseuille’s law?

A

Vessel radius (r)

R= (8ηl) / (πr^4)

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7
Q

Adding resistance beds in series?

A

Increases resistance

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8
Q

Adding resistance beds in parallel?

A

Decreases total resistance

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9
Q

What is the equation for reynolds number?

A

=pdv/η

density, diameter, velocity, viscosity

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10
Q

What would reynolds number be to transition from laminar to turbulent flow?

A

Greater than 2000

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11
Q

Turbulent blood flow can lead to?

A

Bruits and arteriosclerosis

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12
Q

What does compliance of blood vessels describe?

A

How much the vessel expands due to change in lumen hydrostatic pressure

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13
Q

What has more compliance, veins or arteries?

A

Vein

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14
Q

What happens to compliance of arteries as we age?

A

Decrease

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15
Q

Smooth muscle contraction causes a shift in compliance by?

A

Moving blood to arterial side and increasing pressure

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16
Q

The pulsatile nature at aortic end due to compliance and distention during ejection and recoil during diastole is lost by?

A

Arterioles

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17
Q

What is the greatest pressure reached in large arteries?

What is the lowest?

A

1) Systolic pressure

2) Diastolic pressure

18
Q

What does the pulse pressure equal numerically?

A

Systolic - diastolic = 40

19
Q

What does the mean pressure equal numerically?

A

diastolic pressure + 1/3 pulse pressure = 80 + (40/3) = 93.3

20
Q
When there is a decrease in arterial compliance such as from arteriosclerosis, what happens to:
Pulse pressure?
Systolic pressure?
Mean arterial pressure
Diastolic pressure?
A

1) Increases
2) Increases
3) Increases
4) Stay same or decrease

21
Q

What are the features of pressure, compliance, and volume in veins?

A

Low pressure, high compliance, large volume

22
Q

What vessel type is primarily responsible for controlling distribution of blood?

A

Arterioles

23
Q

Where is laminar flow in a vessel?

24
Q

What would the blood viscosity be in an anemic patient?

25
What is the flow rate of blood in the GI system if the arterial pressure is 50 at the beginning the venous pressure is 5 at the end, and the resistance throughout the GI system is 4.5?
10 (50-5)/4.5 Q = ΔP / R
26
Small changes in radius can cause large changes in?
Resistance
27
What does hydrostatic pressure do to fluid? | Osmotic pressure?
1) Pushes out | 2) Pulls in
28
Capillary hydrostatic pressure is what type of force? | What does it do?
1) Positive | 2) Pushes fluid out of capillary
29
Interstitial hydrostatic pressure is what type of force? | What does it do?
1) Negative | 2) Pushes fluid into capillary
30
Capillary osmotic pressure is what type of force? | What does it do?
1) Negative | 2) Pulls fluid into capillary
31
Interstitial osmotic pressure is what type of force? | What does it do?
1) Positive | 2) Pulls fluid into interstitium
32
What startling force is affected in heart failure and DVT? | What does this lead to?
1) Increase of hydrostatic capillary pressure | 2) Movement out of capillary
33
What startling force is affected in malnutrition? | What does this lead to?
1) Decrease of capillary osmotic pressure | 2) Movement out of capillary
34
What startling force is affected in lymphatic obstruction? | What does this lead to?
1) Increase of hydrostatic interstitial pressure | 2) Movement into capillary
35
When does active hyperemia occur?
During exercise when tissue needs more blood flow
36
When does reactive hyperemia occur?
Increase in blood flow in response to a period of ischemia
37
The blood flow to the brain, heart, and active skeletal muscle are controlled by?
Metabolic control
38
The blood flow to the GI and skin are controlled by?
Sympathetic tone (central control)
39
The blood flow to the lungs is controlled by?
Hypoxic vasoconstriction
40
The blood flow to resting skeletal muscle is controlled by?
Central control
41
What is the distribution of blood from the aorta to the various areas: 1) Cerebral 2) Coronary 3) Renal 4) GI 5) Skeletal muscle 6) Skin
1) 15% 2) 5% 3) 25% 4) 25% 5) 25% 6) 5%
42
What effect does aortic stenosis have on BP?
Decreases