Respiratory - Embryology Flashcards

1
Q

When is the pre-embryonic phase?

A

0-3 weeks

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2
Q

When is the embryonic phase?

A

4-8 weeks

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3
Q

When is the foetal phase?

A

9-40 weeks

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4
Q

What is the primitive structure of the respiratory system?

A

Foregut of primitive gut tube

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5
Q

What is the primitive structure of the lung buds?

A

Ventral wall of primitive foregut

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6
Q

What is the primitive structure of the trachea?

A

Ventral wall of primitive foregut

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7
Q

What is the primitive structure of the Ventral trachea and dorsal oesophagus?

A

Oesphagotracheal septum (between these 2 structures separating them)

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8
Q

What is the primitive structure of the lungs?

A

Lung buds (enlarge)

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9
Q

What is the primitive structure of the visceral pleura?

A

Splanchnic layer of lateral plate mesoderm

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10
Q

What is the primitive structure of the parietal pleura?

A

Somatic layer of lateral plate mesoderm

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11
Q

What is the primitive structure of the central tendon of diaphragm?

A

Septum transversum

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12
Q

What grows in from the periphery and fuse with septum transversum?

A

Pleuroperitoneal folds

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13
Q

What is the primitive structure of the muscular part of diaphragm?

A

Skeletal muscle ingrowth from periphery

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14
Q

What is the primitive structure of the diaphragm?

A

Dorsal mesentery of oesphagus

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15
Q

What happens in the following stage?

Embryonic
3-17 weeks

A

Lung buds start to develop as a respiratory diverticulum from the foetal foregut

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16
Q

What happens in the following stage?

Pseudoglandular 7-17 weeks

A

Development of all lung structures exept respiratory part (no gas exchange)

17
Q

What happens in the following stage?

Canalicular 17-27 weeks

A

Formation of respiratory part, Alveolar ducts form and epithelium starts to differentiate into Type I and Type II pneumocytes (still no gas exchange)

18
Q

What happens in the following stage?

A

Saccular 27-40 weeks

Formation of alveolar sacs, primitive alveoli, and surfactant. Gas exchange begins

19
Q

What happens in the following stage?

Alveolar 32 weeks – 8 years

A

Proliferation of alveoli from alveolar sacs.

About 95% of adult alveoli formed postnatally. 300m alveoli in adult