Respiration * Flashcards
what is the thoracic cage composed of ?
sternum, ribs, costal cartilage and thoracic vertebrae
how do ribs join the sternum ?
on the anterior aspect via costal cartilage (also join the vertebrae on the posterior aspect via two joints)
what are two joints that articulate at posterior aspect between ribs and vertebrae ?
costotransverse and costovertebral joints
what are the three types of thoracic muscles ?
- external intercostals
- internal intercostals
- innermost intercostals
describe external intercostlas:
- elevates ribs (inspiration)
- super-lateral to inferomedial
- “hands in your pocket”
which thoracic muscle is used during inspiration ?
external intercostals
describe internal and innermost intercostals :
- depressed ribs (forced expiration)
- superomedial to inferolateral
- “grab your collarbones”
what happens to the diaphragm when contraction occurs ?
- lowers dome
- increases volume of thoracic cavity
which thoracic muscles are used during expiration ?
innermost and internal
what happens to volume when you are breathing in ?
increasing volume
what happens to volume when you are breathing out ?
decreasing volume
increasing volume =
inspiration
decreasing volume =
expiration
why are lungs under tension ?
- naturally want to collapse
- stuck to visceral pleura
alveolar pressure =
atmospheric pressure
what two layers does the pleura have that creates a sac ?
parietal and visceral layers
what is intrapleural pressure ?
around 4 mmHg below atmosphere
when the thoracic cage expands (muscle contraction) what does the parietal pleura do ?
the parietal pleura also contracts… screaming the intrapleural pressure
what is pneumothorax ?
puncture to pleural membrane causes air (pneumo) in pleural space (lung is deflated)
does the intrapleural space pressure change during pneumothorax ?
yes
in what case does the lung no longer go under tension + collapses ?
pneumothorax
if blood is involved in an pneumothorax what is this called ?
hemothorax
what happens if you reseal the hole during an pneumothorax ?
can shift the position of organs in the thorax which can be really problematic
how’s the pressure inside the alveoli during pneunothorax ?
same as atmospheric pressure under normal conditionse
what are two forms of circulation (gas exchange) ?
pulmonary and bronchial
which circulation system supplies the lung tissue ?
bronchial (systemic)
describe the origin of the pulmonary circulation:
deoxygenated blood from the right ventricle
describe the location of the pulmonary circulation:
arteries = center of bronchopulmonary segment
veins = outside of bronchopulmonary segment
describe the features pf the pulmonary circulation:
high flow, low pressure, low resistance
what is the goal of pulmonary circulation ?
oxygenated blood
describe the origin of bronchial circulation :
oxygenated blood from the left ventricle
describe the location of bronchial circulation :
arteries = center of bronchopulmonary segment
veins = drains into pulmonary vein
describe the features of the bronchial circulation :
high pressure and high resistance
describe the goal of bronchial circulation :
perfume lung tissue
what drains via pulmonary vein ?
bronchial artery
the bronchial artery is a part of which circulation ?
systemic circulation
how does the bronchial artery drain its blood ?
originally at the left ventricle, it carries oxygenated blood, under high pressure, to perfuse lung tissue
where does gas exchange occur ?
capillary bed on alveolus
what is the gals of gas exchange ?
oxygenate blood and remove carbon dioxide
how does gas exchange occur ?
this occurs via passive diffusion of these two gasses between the alveoli of your lungs and the pulmonary capillaries carrying blood
what happens when you breathe in ?
oxygen moved into the alveoli and then diffuses across the membrane to get into the capillary; at the same time carbon dioxide present in the capillary is going to move into the alveoli and be breathed out
what are the three zones gas has to pass through ?
- pulmonary capillary
- fused basement membrane
- alveoli
how does oxygen move between the three gas zones ?
alveoli to fused basement membrane to pulmonary capillary
how does carbon dioxide move between the three gas zones ?
pulmonary capillary to fused basement membrane to the alveoli
what is ventilatoin ?
air in alveoli
what is perfusion ?
blood flow through capillaries
what is a shunt ?
adequate perfusion, but no ventilation
what is dead space ?
adequate ventilation, but no perfusion
what causes a shunt ?
pulmonary edema, asthma, COPD, pneumothorax and gas trapping
what causes dead space ?
hemorrhage, dehydration, pulmonary embolism
what is pulmonary edema ?
usually secondary to heart failure
what does it mean if someone has pulmonary edema ?
blood not effectively pumped from left ventricle leads to back up in pulmonary veins and lungs
what are some signs that = fluid accumulation + increased pressure interstitium ?
swelling and eventual leaking of pulmonary capillaries
what happens to diffusion in the case of pulmonary edema ?
diffusion (thus oxygenation) becomes more difficult
if fluid may leak into the pleural cavity (pulmonary effusion) or mediastinum… what does this mean
pulmonary edema
is alveolar flooding possible in the case of pulmonary edema ?
yes and very problematic
what do lungs always want to do ?
lungs always want to collapse (but are held open by the intrapleural pressure)
what does thoracic cage expansion mean ?
intrapleural pressure is decreased therefore lungs expand
what does it mean when pressure drops within the lung tissue ?
air is inspired
what is pneumothorax ?
disruption in pleura (loss of pressure differential and lung collapse)
where does diffusive gas exchange occur ?
between alveoli and pulmonary capillaries