Reproductive System- Taylor Flashcards
When are we genotypically considered male or female?
Conception
Where is the Y (SRY) gene located?
The Yp11 arm of the Y chromosome
When are we phenotypically considered male or female?
7th week of development
Where are the developing genital ridges located?
Around the developing hindgut and it’s mesentery
From what are genital ridges derived?
Endodermal epithelium
Mesodermal mesenchyme
Where do epiblastic germ cells migrate, and what do they form?
From the primitive streak -> gonadal ridges -> form sex cords
In which sex do medullary cords continue to develop?
Males
What do the medullary cords develop into?
The rete testes
What is within the rete testes?
The sustentacular cells of Sertoli
What do the Sertoli cells help with?
Forming the blood-testes barrier
What lies between the rete testes tubules?
The interstitial cells of Leydig
What do the Leydig cells do?
Secrete testosterone by week 8 of development
In which sex do the cortical cords develop?
Female
What do the cortical cords do?
Replace medullary cords
From where do cortical cords arise?
Proliferating epithelium
What do the cortical cords become?
Follicular cells
In which sex does the tunica albuginea develop?
Males
What is the tunica albuginea, and what does it do?
It’s a thick surface layer of developing gonad
It separates the testes cords from the surface epithelium
Why doesn’t the tunica albuginea develop in females?
It allows for the development of the cortical cords
What does the mesonephric duct develop into in males?
Epididymis
Seminal vesicles
Ejaculatory duct
What does the mesonephric duct fuse with in females?
The paramesonephric duct
What does the fusion of the mesonephric and paramesonephric ducts form?
Uterine tubes
Uterus
Cervix
Upper vagina
In XY, the genital tubercle develops into:
: the penis
In XY, the urethral folds come together to form:
: the shaft of the penis
In XY, the genital swellings form the:
: scrotum