Nutrition- Fitz Flashcards

0
Q

BMR

A

Basal metabolic rate

- for counting calories, without the right caloric intake the body uses up its fats and muscles

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1
Q

BMI

A

Body mass index

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2
Q

What’s the best type of DL?

A

HDL

- the others contribute to atherosclerosis

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3
Q

TPN

A

Total peripheral nutrition

- for people whose digestive system is shut down, inserted at subclavian, gives the body it’s nutrition

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4
Q

From where is cholesterol derived?

A

Diet: excreted in feces
Liver: secretion into bile, formation of bile salts

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5
Q

What happens to most of blood glucose?

A

Goes to brain

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6
Q

End products of postabsorptive state:

A

: Glucose to nervous tissue
FAs -> energy, CO2, water to most tissues, excluding nervous
Ketones -> energy, CO2, water to most tissues, including nervous

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7
Q

Increased plasma insulin: absorptive state in muscle

A

Increased glucose uptake
Glycogen synthesis
AA uptake
Protein synthesis

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8
Q

Increased plasma insulin: absorptive state in adipocytes

A

Increased glucose uptake

Triglyceride synthesis

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9
Q

Increased plasma insulin: absorptive state in the liver

A

Decreased gluconeogenesis
Glycogen synthesis
Triglyceride synthesis
No ketone synthesis

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10
Q

Where are insulin target tissue receptors located?

A

Muscle
Adipocytes
Liver

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11
Q

High glucose levels results in:

A

: insulin secretion from the pancreas beta cells

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12
Q

Low glucose levels result in:

A

: glucagon secretion by the alpha cells in the pancreas

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13
Q

What are incretins?

A

Insulin-associated proteins that stimulate pancreas beta cells to secrete insulin

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14
Q

What inhibits the secretion of insulin from the pancreas beta cells?

A

Sympathetic activity -> plasma EP

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15
Q

DM I

A

Juvenile onset

Immune system attacks beta cells

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16
Q

DM II

A

Ineffective insulin receptor

Lethargic with low glucose

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17
Q

What is the sympathetic response to low glucose?

A

Adrenal medulla stimulated to secrete EP
Increased activity of sympathetic nerves in liver and adipose
Results in increase in plasma glucose, FAs, and glycerol

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18
Q

Effects of EP on insulin and glucagon:

A

: Negative effect on insuli

Positive effect on glucagon

19
Q

What do basal concentrations of cortisol allow for?

A

Stimulation of gluconeogenesis and lipolysis in the postabsorptive state

20
Q

Increased cortisol concentrations in plasma:

A

: Increased protein catabolism
Increased gluconeogenesis
Decreased glucose uptake
Increased triglyceride breakdown

21
Q

Growth hormone is similar to ______ and opposite ______.

A

Cortisol

Insulin

22
Q

Gluconeolysis regulators

A

Glucagon

EP

23
Q

Gluconeogenesis regulators

A

Glucagon, EP, cortisol, GH

24
Lipolysis regulators
EP, cortisol, GH
25
Inhibition of glucose uptake regulators
Cortisol, GH
26
Exercise and stress
Decreased glucose (being uptaken) Increased glucagon Decreased insulin Decreased cortisol
27
Total energy =
Energy released as heat + energy to perform work
28
Things that decrease BMR:
: Sleep Increased age Being a female Fasting (to conserve energy)
29
Energy from food intake=
Internal heat produced + external work + energy stored
30
What is leptin?
A secretant that alters hypothalamic centers to control energy stores (and also appetite)
31
How are ghrelin and leptin related?
They're opposite one another. | Ghrelin stimulates hunger while leptin inhibits it.
32
Relation of increased fat with increased blood pressure:
: Increased fat -> increased vasculature -> increased resistance -> increased blood pressure
33
What are pyrogens?
The cause of fever. They raise temp to combat an infection. They're secreted by the liver and macrophages
34
What is hypoglycemia?
Abnormally low plasma glucose concentration
35
Assembly
Anabolism
36
Breakdown
Catabolism
37
Molecules within the arcuate nucleus that are targeted by leptin:
: Alpha MSH | Cart
38
Syndrome affecting lateral hypothalamus:
Anorexia
39
Syndrome affecting ventral medial hypthalamus:
Obesity | -faulty leptin receptors
40
Products of anabolism and catabolism in energy balance:
: Glucose FAs Triglycerides
41
What does leptin do?
It regulates body mass by decreasing appetite and increasing energy expenditure
42
What happens during leptin depletion?
Adaptive response to fight starvation
43
Nuclei that leptin affects:
Lateral hypothalamic (2) Arcuate Periventricular
44
What does brown adipose do?
More common in children and Arctic-residing population | Heat production and insulation