reproductive path Flashcards

1
Q

XXY

A

kleinfelter’s

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2
Q

signs of kleinfelter’s

A

testicular atrophy, eunichoid body shape, tall, long extremities, female hair distribution - developmental delay

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3
Q

XO

A

turner’s syndrome

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4
Q

signs of turner’s

A

short, streak ovary, sheild chest, bicuspid aortic valve, webbing of neck,

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5
Q

heart defect in turner’s

A

infantile coarctation

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6
Q

causes menopause before menarche

A

turner’s

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7
Q

XYY signs

A

phenotyically normal, very tall with severe acne, possibly anti social or autistic

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8
Q

causes female pseudohermaphrodites

A

excessive and innapropriate esposure to andorgens during early gestation

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9
Q

causes male pseudohermaphrodites

A

androgen insensitivity syndrome

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10
Q

47, XXY

A

true hermaphrodism

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11
Q

signs of androgen insenstivity

A

female external genetalia with rudimentary vagina. No internal genetalia, streak testes (must be removed) high testosterone, estogen and LH

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12
Q

signs of 5a reductase deficiency

A

males - ambiguois genetalia at puberty, then testosterone casues masculizination normal internal genetalia

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13
Q

kallman syndrome

A

anosima, lack of 2ndary sexual chaeracteristics,

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14
Q

causes kallman

A

defective migration of GnRH cells, no GnRH in hypothalmis. all hormones, testosterone and sperm count are low

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15
Q

complete mole chromosomes

A

46 XX/XY

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16
Q

partial mole chromosomes

A

69 XXX/XXY/XYY

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17
Q

mole with very high HCG

A

complete

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18
Q

mole that can covert to choriocarcinoma

A

partial

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19
Q

mole with fetal parts

A

partial

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20
Q

high risk of cancer with this mole

A

complete

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21
Q

cluster of grapes

A

complete mole

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22
Q

snowstorm on sonogram mole

A

partial

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23
Q

tx for mole

A

D and C + methotrexate with monitoring of hGC

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24
Q

what makes preeclampsia into eclampsia

A

precense of seizures

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25
Q

preclampsia before 20 weeks may be

A

mole

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26
Q

HELLP syndrome

A

hemolysis, liver failure with eclampsia

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27
Q

risk factors for preeclampsia

A

hypertension, diabetes, chronic renal dx, autoimmune disorders

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28
Q

sx of preeclampsia

A

headache, blurred vision, edema of face and extremities, hyperreflexia

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29
Q

risks of placental abrubtion

A

smoking hypertension, cocaine use

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30
Q

signs of placental abruption

A

painful abrubt bleeding in 3rd trimester

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31
Q

placenta previa

A

attachment of pacenta to lower uterus and os

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32
Q

sx of placenta previa

A

painless bleeding at anytime

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33
Q

risk for ectopic

A

hx of infertility, PID, ruptured appendix, prior tubal surgery

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34
Q

can casue polyhydromanios

A

espohageal/duodenal atresia (cant swallow fluid)

35
Q

can cause oligohydraminios

A

fetal kidney/ureter defect

36
Q

virus causing cervical carcinoma

A

HPV 16/18 (16 - inhibits p53/18 inibits RB)

37
Q

tx for endometriosis

A

OCP, NSAIDS, leuporolide, danazol

38
Q

endometrium within myometrium

A

adenomyosis (tx with hysterectomy)

39
Q

postmenopausal vaginal bleeding

A

endometrial hyperplasia or carcinoma

40
Q

most common tumor in females

A

leiomyoma

41
Q

beginin endometrial smooth muscle tumor

A

leiomyoma

42
Q

cancerous myometrial tumor

A

leiomyosarcoma (very agressive)

43
Q

hormone findings in premature ovarian failure

A

low estrogen, high LH/FSH

44
Q

most common causes of lack of ovulation

A

pregnancy, PCOS, obesity, HPO axis abmormalities, premature ovarian failure, cushings, adrenal falure, thyroid/easting disorders,

45
Q

risks for PCOS

A

insulin resistance, obesity

46
Q

tx for PCOS

A

low dose OCPs, spirolactone, clomiphine, metformin

47
Q

chocolate cyst

A

endometriosis

48
Q

most common ovarian mass in young women

A

follicular cyst

49
Q

most common ovarian tumor in adolecents

A

germ cell tumors

50
Q

ovarian tumor associated with Turner’s syndrome

A

dysgerminoma

51
Q

aggressive ovarian tumor in young girls

A

yolk sac tumor

52
Q

yolk sac tumor marker

A

AFP

53
Q

aggresivly malignant tetroma

A

immature tetroma

54
Q

general ovarian cancer marker

A

CA-125

55
Q

genetic risk factors for ovarian cancer

A

BRCA, HNPCC, family hx

56
Q

most common benign ovarian tumor

A

serous cystademoma

57
Q

most common malignant ovarian tumor

A

serous cystenadocarcinoma (often bilateral)

58
Q

ovarian tumor that can cause precocious puberty

A

granulosa cell tumor

59
Q

vaginal tumor in kids

A

sarcoma botryodies

60
Q

most common breast tumor in young women

A

fibroademma

61
Q

small, mobile firm mass that is sensitive to menstrual cycle

A

fibroademoma

62
Q

benign tumor with slight risk for carcinoma

A

intraductal papilloma

63
Q

serous or bloody discharge in benign tumor

A

intraductal papilloma

64
Q

most important prognostic indicator in breast cancer

A

axilary node involbement

65
Q

risk factors in breast cancer

A

family hx, obesity, early menarche, late first birth

66
Q

ductal cancer with caseous necrosis

A

comedocarcinoma

67
Q

firm, fibrous, rock-hard cancer with glandularcells

A

invasive ductal cancer

68
Q

worst, most common brest cancer

A

invasive ductal

69
Q

breast cancer with orderly rows of cells

A

invasive lobular

70
Q

best prognosis in breast cancer

A

medullary

71
Q

peau d;orange type breast cancer

A

inflammaroty

72
Q

fibrocystic dx with risk of developing cancer

A

epithelial hyperplasia

73
Q

can cause gynomastia in males

A

hyperestrogenism (cirrosis, testicular tumor, puberty, old age), drugs( estrogen, pot, spirolactone, digitalis, alchohol, ketoconazole)

74
Q

tx for BPH

A

terazosin, tamulosin, finesteride

75
Q

where prostate cancer develops

A

posterior lobe

76
Q

tumor markers for prostate cancer

A

PSA and PAP

77
Q

signs of metastatic prostate cancer

A

lower back pain, high PSA and alkaline phosphatase

78
Q

side usually getting varicoele

A

left (from resitance to flow of the renal vein)

79
Q

testicular cancer that produces HCG

A

choriocarcinoma

80
Q

painful testicular cancer with poor prognosis

A

embryonal

81
Q

testicular cancer that produces HCG and SFP

A

embryonal

82
Q

testicular cancer that metastizes to lungs

A

choriocarcinoma

83
Q

most common testicuar cancer in young makes

A

seminoma

84
Q

seminoma tumor marker

A

PLAP