Path - CV Flashcards

1
Q

congenital right to left shunts

A
Tetralogy of Fallot
Transposition of the Great Arteries
Persistant Truncus arteriosus
Tricuspid Atresia
Total anomalous pulmonary venous return
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2
Q

most common Congenital Heart defect

A

VSD

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3
Q

left to right congenital shunts

A

VSD, ASD, PDA

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4
Q

tetralogy defects

A

pulmonary stenosis (most important prognosis factor)
RV hypertrophy
overriding aorta
VSD

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5
Q

type of coarctication of the aorta associated with rib notching

A

adult (distal to ductus)

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6
Q

Turner’s syndrome heart defect

A

infantile coarct of aorta

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7
Q

22q11 heart defect

A

trunctus, Tertology

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8
Q

down syndrome heart defect

A

and endocardial cushion defect

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9
Q

congential rubella heart defect

A

septal defects, PDA, pulmonary artery stenosis

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10
Q

marfan’s syndrome heart defect

A

aortic insufficiency and dissection

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11
Q

infanct of diabetic mother heart defect

A

transpostion

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12
Q

cause of primary hypertension

A

CO or peripherial pressure

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13
Q

calcification in the media of arteries - usual radial or ulnar

A

monckeberg

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14
Q

progression of atherosclerosis

A

endotheial cell dysfunction –> macrophage and LDL accunmulation –> foam cell formation –> fatty streaks –> smooth cell migration –> proliferation –> fibrous plauqe –> complex atheroma

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15
Q

most common site of atherosclorotic plaque

A

abdominal aorta

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16
Q

stable/unstable angina shows on ECG

A

ST depression

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17
Q

ST elevation and angina at rest

A

prinzmetal’s

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18
Q

most common coronary ateery occlusion

A

LAD>RCA>Cfx

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19
Q

time frame that MI shows early coag necrosis, edema, hemorage and wavy fibers

A

4-12 hrs

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20
Q

time frame that MI shows beginning of neutrophil migration

A

12-24 hours

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21
Q

risk in post MI days 3-14

A

free wall rupture leading to tamponade

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22
Q

time frame that MI shows macrophage infiltration

A

3-14days

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23
Q

causes contraction bands post MI

A

reperfusion syndrome

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24
Q

when does Cardiac troponin rise post MI

A

after 4 hours, and eevated fr 7-10 days

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25
dx of reinfarction following acute MI
CK-MB
26
ECG changes in MI
ST elevation ST depression (subendocardial infacrct) pathologic Q waves
27
Q wave in V1-V4
LAD/anterior infarct
28
Q wave in V1-V2
LAD/anteroseptal wall
29
Q wave in V4-V6
LCX
30
Q wave in I, aVL
LCX/lateral wall
31
Q wave in II,III, aVF
RCA/inferior wall
32
dressler's syndrome
autoimmune phenom resulting in fibrous pericarditis
33
cause of dilated cardiomyopathy
alchohol abuse, wet beriberi, coxsackie B, cocaine, chagas dx, doxorubicin
34
tx for dilated cardiomyopathy
reduce sodium, ACEi, diuretics, dig, transplant
35
sarcomeres added in series
dilated cardiomyopathy
36
causes of hypertrophic myopathy
mostly familial (AD) - heavy chain B-myosin mutation
37
tx for hypertrophic myopathy
CCB, B blocker
38
sarcomeres added in parellel
hypertrophic myopathy
39
sx of hypertrophic myopathy
systolic murmur, S4, syncopal episodes, sudden death
40
reduce mortality n CHF
ACEi, B blockers, angiotensin receptor antagonist, spirolactone
41
Do NOT give to acute decompensated CHF
B blockers
42
signs of L HF
pulmonary edema, paroxysmal nocternal dyspena, SOB
43
signs of R HF
hepatomegaly, peripheral edema, JVD
44
signs of bacterial endocarditis
fever, roth's spots in retina, osler's nodes, janeway lesions, splinter hemorrgahes
45
bug causing acute bacterial endocarditis
staph A
46
bug causing subacute bacterial endocarditis
viridins strepto
47
vavle damaged by endocarditis secondary to IV use
trcuspid
48
most common valve damaged in bacterial endocarditis
mitral
49
bug causeing pheumatic fever
strep (group A beta hemolytic) postpharyngeal infection
50
ECG changes in acute pericarditis
widespread ST elevevation and PR depression
51
causes serous pericarditis
viral, autoimmune dxs
52
presents with loud friction rub
fibrinous pericarditis
53
most common cardiac tumor in adults
myxoma (ball-valve can cause fainting)
54
most common cardiac tumor in kids
rhabdomyoma
55
kussmaul's sign
increase in JVP in inspiration (from pericarditis, restrictive cariomyopathy, tumros, tamponade)
56
vasculitis: young asian females, pulseless in BLE, nigh sweats, nightsewats
takayasu arteritis (granulomatus thickening in aortic arch)
57
high sed rates can be
temporal/takayasu arteritis (treat with high dose corticosteroids)
58
vasculitis constitutional sx, melana, renal damage. Hep B seropositivity
polyateritis nodosa (immune complex) affects visceral and renal vessels
59
young asian kids with strawberry toundm fever, desquaminating rash and coronary aneurysms
kawasaki dx. -
60
vasculitis in smokers
beurger's (thromboangititis obliterans)
61
P-ANCA postitive vasculitis involving lung, kidneys and skin
microscopic polyangiitis
62
triad of local necrotising vasculitis, necrotixzing granulomas in lung and upper airway, necrotizing glomularnephritis. c-ANCA +
wegener's granulomatosis
63
asthmas, sinutisus, purpura, peripheral neuropathy. p-ANCA and elevated IgE
churg-strauss
64
purpua on buttocks and legs, arthalgia, abdomonal pain and melena
henoch-schonlein purpura - vasculitis secondary to IgA depostition
65
lymphatic malignancy associated with persistent lymphedema
lymphangiosarcoma
66
blood vessel malignancy associated with radiation therapy
angiosarcoma
67
port-wine stain, intracerebral AVM, and early onset glaucoma
sturge-weber