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Step 1 - Path > path-onc > Flashcards

path-onc Flashcards

1
Q

lyphoma with localized group of node involvement with contiguous spread

A

hodgkin’s

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2
Q

lyphoma with redd-sternberg cells

A

hodgkin’s

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3
Q

ages of hodgkin’s

A

young adulthood and over 55

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4
Q

virus associated with Hodgkin’s

A

EBV

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5
Q

lymphoma with B sx

A

hodgkin’s

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6
Q

non-hoddgkin’s cell type

A

B cell (mostly)

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7
Q

age of non hodkin’s

A

most types 20-40 years

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8
Q

best prognosis type of lymphoma

A

nodulat schlerosing

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9
Q

reed sternberg cell CD type

A

30 and 15 B cells

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10
Q

burkitt’s gene defect

A

8;14 c-myc

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11
Q

mantle cell gene defect

A

11;14

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12
Q

follicular lymphoma gene defect

A

14;18 bcl-2

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13
Q

starry sky, EBV sheets of lyphocytes

A

burkitt’s

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14
Q

mst common adult NHL

A

diffuse B cell

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15
Q

prognosis of mantle cell Lymphoma

A

very poor

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16
Q

aggressive lyphoma caused by HTLV-1

A

adult T cell

17
Q

population in adult T cell

A

japan, W africa, caribbean

18
Q

CD4+ cutaneuous patche/nodules

A

mycosis fungoides

19
Q

fried egg cell producing lots of IgG and I gA

A

multiple myeloma

20
Q

signs of Multiple myeloma

A

hypercalcemia
renal insiff
anemia
bone lesions (back pain)

21
Q

spiked protein in Multiple Myeloma

A

M

22
Q

ALL gene with good prognosis

A

12;21

23
Q

LOTS of blood ad bone marrow lymphoblasts in kid under 15

A

ALL

24
Q

smudge cells in peripheral blood smear in old peopls

A

CLL

25
Q

stain for Hairy cell

A

TRAP

26
Q

tx for Hairy cell

A

cladribine

27
Q

auer rods

A

AML

28
Q

lots of cirulating myeoblasts in adults, and possible DIC

A

AML

29
Q

gene defect in AML

A

15;17

30
Q

philly chromosome

A

CML (9;22)

31
Q

myeloid stem cell proliferation with lots of neutrophils, ans basophils and splenomegaly

A

CML

32
Q

CML may progress to

A

AML/ALL (blast crisis)

33
Q

good tx for CL

A

imatinib

Step 1 - Path (12 decks)

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