path-onc Flashcards

1
Q

lyphoma with localized group of node involvement with contiguous spread

A

hodgkin’s

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2
Q

lyphoma with redd-sternberg cells

A

hodgkin’s

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3
Q

ages of hodgkin’s

A

young adulthood and over 55

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4
Q

virus associated with Hodgkin’s

A

EBV

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5
Q

lymphoma with B sx

A

hodgkin’s

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6
Q

non-hoddgkin’s cell type

A

B cell (mostly)

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7
Q

age of non hodkin’s

A

most types 20-40 years

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8
Q

best prognosis type of lymphoma

A

nodulat schlerosing

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9
Q

reed sternberg cell CD type

A

30 and 15 B cells

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10
Q

burkitt’s gene defect

A

8;14 c-myc

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11
Q

mantle cell gene defect

A

11;14

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12
Q

follicular lymphoma gene defect

A

14;18 bcl-2

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13
Q

starry sky, EBV sheets of lyphocytes

A

burkitt’s

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14
Q

mst common adult NHL

A

diffuse B cell

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15
Q

prognosis of mantle cell Lymphoma

A

very poor

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16
Q

aggressive lyphoma caused by HTLV-1

A

adult T cell

17
Q

population in adult T cell

A

japan, W africa, caribbean

18
Q

CD4+ cutaneuous patche/nodules

A

mycosis fungoides

19
Q

fried egg cell producing lots of IgG and I gA

A

multiple myeloma

20
Q

signs of Multiple myeloma

A

hypercalcemia
renal insiff
anemia
bone lesions (back pain)

21
Q

spiked protein in Multiple Myeloma

22
Q

ALL gene with good prognosis

23
Q

LOTS of blood ad bone marrow lymphoblasts in kid under 15

24
Q

smudge cells in peripheral blood smear in old peopls

25
stain for Hairy cell
TRAP
26
tx for Hairy cell
cladribine
27
auer rods
AML
28
lots of cirulating myeoblasts in adults, and possible DIC
AML
29
gene defect in AML
15;17
30
philly chromosome
CML (9;22)
31
myeloid stem cell proliferation with lots of neutrophils, ans basophils and splenomegaly
CML
32
CML may progress to
AML/ALL (blast crisis)
33
good tx for CL
imatinib